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Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly.
Rodriguez-Laguna L, Agra N, Ibañez K, Oliva-Molina G, Gordo G, Khurana N, Hominick D, Beato M, Colmenero I, Herranz G, Torres Canizalez JM, Rodríguez Pena R, Vallespín E, Martín-Arenas R, Del Pozo Á, Villaverde C, Bustamante A, Ayuso C, Lapunzina P, Lopez-Gutierrez JC, Dellinger MT, Martinez-Glez V. Rodriguez-Laguna L, et al. Among authors: agra n. J Exp Med. 2019 Feb 4;216(2):407-418. doi: 10.1084/jem.20181353. Epub 2018 Dec 27. J Exp Med. 2019. PMID: 30591517 Free PMC article.
CLAPO syndrome: identification of somatic activating PIK3CA mutations and delineation of the natural history and phenotype.
Rodriguez-Laguna L, Ibañez K, Gordo G, Garcia-Minaur S, Santos-Simarro F, Agra N, Vallespín E, Fernández-Montaño VE, Martín-Arenas R, Del Pozo Á, González-Pecellín H, Mena R, Rueda-Arenas I, Gomez MV, Villaverde C, Bustamante A, Ayuso C, Ruiz-Perez VL, Nevado J, Lapunzina P, Lopez-Gutierrez JC, Martinez-Glez V. Rodriguez-Laguna L, et al. Among authors: agra n. Genet Med. 2018 Aug;20(8):882-889. doi: 10.1038/gim.2017.200. Epub 2018 Feb 15. Genet Med. 2018. PMID: 29446767 Free article.
Capillary malformation with segmental distribution and central atrophy: A series of 7 cases.
Ivars M, Azaña JM, Weibel L, Theiler M, Boixeda P, Norris DI, Martinez-Glez V, Agra N, Rodríguez-Laguna L, Colmenero I, Beato-Merino MJ, López-Gutiérrez JC. Ivars M, et al. Among authors: agra n. J Am Acad Dermatol. 2020 Jul;83(1):213-214. doi: 10.1016/j.jaad.2019.09.016. Epub 2019 Sep 18. J Am Acad Dermatol. 2020. PMID: 31541744 No abstract available.
NOD1 receptor is up-regulated in diabetic human and murine myocardium.
Prieto P, Vallejo-Cremades MT, Benito G, González-Peramato P, Francés D, Agra N, Terrón V, Gónzalez-Ramos S, Delgado C, Ruiz-Gayo M, Pacheco I, Velasco-Martín JP, Regadera J, Martín-Sanz P, López-Collazo E, Boscá L, Fernández-Velasco M. Prieto P, et al. Among authors: agra n. Clin Sci (Lond). 2014 Dec;127(12):665-77. doi: 10.1042/CS20140180. Clin Sci (Lond). 2014. PMID: 24934088
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p.
Brea R, Motiño O, Francés D, García-Monzón C, Vargas J, Fernández-Velasco M, Boscá L, Casado M, Martín-Sanz P, Agra N. Brea R, et al. Among authors: agra n. Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):325-337. doi: 10.1016/j.bbadis.2017.11.001. Epub 2017 Nov 3. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29109031 Free article.
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