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Agreement between TOAST and CCS ischemic stroke classification: the NINDS SiGN study.
McArdle PF, Kittner SJ, Ay H, Brown RD Jr, Meschia JF, Rundek T, Wassertheil-Smoller S, Woo D, Andsberg G, Biffi A, Brenner DA, Cole JW, Corriveau R, de Bakker PI, Delavaran H, Dichgans M, Grewal RP, Gwinn K, Huq M, Jern C, Jimenez-Conde J, Jood K, Kaplan RC, Katschnig P, Katsnelson M, Labovitz DL, Lemmens R, Li L, Lindgren A, Markus HS, Peddareddygari LR, Pedersén A, Pera J, Redfors P, Roquer J, Rosand J, Rost NS, Rothwell PM, Sacco RL, Sharma P, Slowik A, Sudlow C, Thijs V, Tiedt S, Valenti R, Worrall BB; NINDS SiGN Study. McArdle PF, et al. Neurology. 2014 Oct 28;83(18):1653-60. doi: 10.1212/WNL.0000000000000942. Epub 2014 Sep 26. Neurology. 2014. PMID: 25261504 Free PMC article.
OBJECTIVE: The objective of this study was to assess the level of agreement between stroke subtype classifications made using the Trial of Org 10172 Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (C
OBJECTIVE: The objective of this study was to assess the level of agreement between stroke subtype classifications
Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke.
von Berg J, van der Laan SW, McArdle PF, Malik R, Kittner SJ, Mitchell BD, Worrall BB, de Ridder J, Pulit SL. von Berg J, et al. Eur J Hum Genet. 2020 Jul;28(7):963-972. doi: 10.1038/s41431-020-0580-5. Epub 2020 Feb 11. Eur J Hum Genet. 2020. PMID: 32047268 Free PMC article.
The most commonly used systems are TOAST (Trial of Org 10172 in Acute Stroke Treatment) and CCS (Causative Classification System for Stroke), but agreement is only moderate. We have compared two approaches to combining the existing subtyp …
The most commonly used systems are TOAST (Trial of Org 10172 in Acute Stroke Treatment) and CCS (Causative Classific