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Page 1
Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes.
Martínez-Redondo V, Jannig PR, Correia JC, Ferreira DM, Cervenka I, Lindvall JM, Sinha I, Izadi M, Pettersson-Klein AT, Agudelo LZ, Gimenez-Cassina A, Brum PC, Dahlman-Wright K, Ruas JL. Martínez-Redondo V, et al. Among authors: agudelo lz. J Biol Chem. 2016 Jul 15;291(29):15169-84. doi: 10.1074/jbc.M115.705822. Epub 2016 May 26. J Biol Chem. 2016. PMID: 27231350 Free PMC article.
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.
Pettersson-Klein AT, Izadi M, Ferreira DMS, Cervenka I, Correia JC, Martinez-Redondo V, Southern M, Cameron M, Kamenecka T, Agudelo LZ, Porsmyr-Palmertz M, Martens U, Lundgren B, Otrocka M, Jenmalm-Jensen A, Griffin PR, Ruas JL. Pettersson-Klein AT, et al. Among authors: agudelo lz. Mol Metab. 2018 Mar;9:28-42. doi: 10.1016/j.molmet.2018.01.017. Epub 2018 Feb 3. Mol Metab. 2018. PMID: 29428596 Free PMC article.
Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation.
Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR, Pettersson-Klein AT, Lakshmikanth T, Sustarsic EG, Porsmyr-Palmertz M, Correia JC, Izadi M, Martínez-Redondo V, Ueland PM, Midttun Ø, Gerhart-Hines Z, Brodin P, Pereira T, Berggren PO, Ruas JL. Agudelo LZ, et al. Cell Metab. 2018 Feb 6;27(2):378-392.e5. doi: 10.1016/j.cmet.2018.01.004. Cell Metab. 2018. PMID: 29414686 Free article.
Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.
Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL. Agudelo LZ, et al. Cell. 2014 Sep 25;159(1):33-45. doi: 10.1016/j.cell.2014.07.051. Cell. 2014. PMID: 25259918 Free article.
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.
Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL. Correia JC, et al. Among authors: agudelo lz. Mol Metab. 2015 Sep 26;4(12):891-902. doi: 10.1016/j.molmet.2015.09.005. eCollection 2015 Dec. Mol Metab. 2015. PMID: 26909306 Free PMC article.
Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation.
Mills R, Taylor-Weiner H, Correia JC, Agudelo LZ, Allodi I, Kolonelou C, Martinez-Redondo V, Ferreira DMS, Nichterwitz S, Comley LH, Lundin V, Hedlund E, Ruas JL, Teixeira AI. Mills R, et al. Among authors: agudelo lz. Mol Metab. 2018 Jan;7:12-22. doi: 10.1016/j.molmet.2017.11.001. Epub 2017 Nov 7. Mol Metab. 2018. PMID: 29157948 Free PMC article.
LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force.
Ferreira DMS, Cheng AJ, Agudelo LZ, Cervenka I, Chaillou T, Correia JC, Porsmyr-Palmertz M, Izadi M, Hansson A, Martínez-Redondo V, Valente-Silva P, Pettersson-Klein AT, Estall JL, Robinson MM, Nair KS, Lanner JT, Ruas JL. Ferreira DMS, et al. Among authors: agudelo lz. Skelet Muscle. 2019 Oct 31;9(1):26. doi: 10.1186/s13395-019-0214-1. Skelet Muscle. 2019. PMID: 31666122 Free PMC article.
Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans.
Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, Kamandulis S, Ruas JL, Erhardt S, Westerblad H, Andersson DC. Schlittler M, et al. Among authors: agudelo lz. Am J Physiol Cell Physiol. 2016 May 15;310(10):C836-40. doi: 10.1152/ajpcell.00053.2016. Epub 2016 Mar 30. Am J Physiol Cell Physiol. 2016. PMID: 27030575 Free article. Clinical Trial.
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