Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

49 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase.
Agudo R, Calvo PA, Martínez-Jiménez MI, Blanco L. Agudo R, et al. Nucleic Acids Res. 2017 Sep 6;45(15):9046-9058. doi: 10.1093/nar/gkx633. Nucleic Acids Res. 2017. PMID: 28911121 Free PMC article.
Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus.
Perales C, Agudo R, Manrubia SC, Domingo E. Perales C, et al. Among authors: agudo r. J Mol Biol. 2011 Mar 18;407(1):60-78. doi: 10.1016/j.jmb.2011.01.026. Epub 2011 Jan 19. J Mol Biol. 2011. PMID: 21256131
Here we report a study involving the mutagenesis of foot-and-mouth disease virus (FMDV) by the nucleoside analogue ribavirin (R) and the effect of R-mediated mutagenesis on the selection of FMDV mutants resistant to the inhibitor of RNA replication, guanidine hydroc …
Here we report a study involving the mutagenesis of foot-and-mouth disease virus (FMDV) by the nucleoside analogue ribavirin (R) and …
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Agudo R, Ferrer-Orta C, Arias A, de la Higuera I, Perales C, Pérez-Luque R, Verdaguer N, Domingo E. Agudo R, et al. PLoS Pathog. 2010 Aug 26;6(8):e1001072. doi: 10.1371/journal.ppat.1001072. PLoS Pathog. 2010. PMID: 20865120 Free PMC article.
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin.
Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I, Arias A, Pérez-Luque R, Escarmís C, Domingo E, Verdaguer N. Ferrer-Orta C, et al. Among authors: agudo r. J Virol. 2010 Jun;84(12):6188-99. doi: 10.1128/JVI.02420-09. Epub 2010 Apr 14. J Virol. 2010. PMID: 20392853 Free PMC article.
Passage of poliovirus (PV) or foot-and-mouth disease virus (FMDV) in the presence of ribavirin selected for viruses with decreased sensitivity to R, which included different mutations in their polymerase (3D): G64S located in the finger subdomain in the case of PV and M296 …
Passage of poliovirus (PV) or foot-and-mouth disease virus (FMDV) in the presence of ribavirin selected for viruses with decreased sensitivi …
Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment.
Perales C, Agudo R, Domingo E. Perales C, et al. Among authors: agudo r. PLoS One. 2009;4(5):e5554. doi: 10.1371/journal.pone.0005554. Epub 2009 May 14. PLoS One. 2009. PMID: 19436746 Free PMC article.
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.
Agudo R, Arias A, Pariente N, Perales C, Escarmís C, Jorge A, Marina A, Domingo E. Agudo R, et al. J Mol Biol. 2008 Oct 10;382(3):652-66. doi: 10.1016/j.jmb.2008.07.033. Epub 2008 Jul 17. J Mol Biol. 2008. PMID: 18662697
Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe.
Sierra M, Airaksinen A, González-López C, Agudo R, Arias A, Domingo E. Sierra M, et al. Among authors: agudo r. J Virol. 2007 Feb;81(4):2012-24. doi: 10.1128/JVI.01606-06. Epub 2006 Dec 6. J Virol. 2007. PMID: 17151116 Free PMC article.
The nucleoside analogue ribavirin (R) is mutagenic for foot-and-mouth disease virus (FMDV). Passage of FMDV in the presence of increasing concentrations of R resulted in the selection of FMDV with the amino acid substitution M296I in the viral polymerase (3D). Measu …
The nucleoside analogue ribavirin (R) is mutagenic for foot-and-mouth disease virus (FMDV). Passage of FMDV in the presence of increa …
Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding.
Arias A, Agudo R, Ferrer-Orta C, Pérez-Luque R, Airaksinen A, Brocchi E, Domingo E, Verdaguer N, Escarmís C. Arias A, et al. Among authors: agudo r. J Mol Biol. 2005 Nov 11;353(5):1021-32. doi: 10.1016/j.jmb.2005.09.022. Epub 2005 Sep 26. J Mol Biol. 2005. PMID: 16216271
Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase.
Ferrer-Orta C, Agudo R, Domingo E, Verdaguer N. Ferrer-Orta C, et al. Among authors: agudo r. Curr Opin Struct Biol. 2009 Dec;19(6):752-8. doi: 10.1016/j.sbi.2009.10.016. Epub 2009 Nov 13. Curr Opin Struct Biol. 2009. PMID: 19914060 Review.
49 results
Jump to page
Feedback