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Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.
Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E, Iglesias GN, Shokat L, Tripathi S, Balasubramaniam V, Webb LG, Aguirre S, Willsey AJ, Garcia-Sastre A, Pollard KS, Cherry S, Gamarnik AV, Marazzi I, Taunton J, Fernandez-Sesma A, Bellen HJ, Andino R, Krogan NJ. Shah PS, et al. Among authors: aguirre s. Cell. 2018 Dec 13;175(7):1931-1945.e18. doi: 10.1016/j.cell.2018.11.028. Cell. 2018. PMID: 30550790 Free PMC article.
Innate immunity evasion by Dengue virus.
Morrison J, Aguirre S, Fernandez-Sesma A. Morrison J, et al. Among authors: aguirre s. Viruses. 2012 Mar;4(3):397-413. doi: 10.3390/v4030397. Epub 2012 Mar 15. Viruses. 2012. PMID: 22590678 Free PMC article. Review.
Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.
Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs D, Hamilton J, Leon PE, Chawdury A, Tripathi S, Melegari C, Campisi L, Hai R, Metreveli G, Gamarnik AV, García-Sastre A, Greenbaum B, Simon V, Fernandez-Sesma A, Krogan NJ, Mulder LCF, van Bakel H, Tortorella D, Taunton J, Palese P, Marazzi I. Heaton NS, et al. Among authors: aguirre s. Immunity. 2016 Jan 19;44(1):46-58. doi: 10.1016/j.immuni.2015.12.017. Immunity. 2016. PMID: 26789921 Free PMC article.
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.
Aguirre S, Luthra P, Sanchez-Aparicio MT, Maestre AM, Patel J, Lamothe F, Fredericks AC, Tripathi S, Zhu T, Pintado-Silva J, Webb LG, Bernal-Rubio D, Solovyov A, Greenbaum B, Simon V, Basler CF, Mulder LC, García-Sastre A, Fernandez-Sesma A. Aguirre S, et al. Nat Microbiol. 2017 Mar 27;2:17037. doi: 10.1038/nmicrobiol.2017.37. Nat Microbiol. 2017. PMID: 28346446 Free PMC article.
Dengue virus genomic variation associated with mosquito adaptation defines the pattern of viral non-coding RNAs and fitness in human cells.
Filomatori CV, Carballeda JM, Villordo SM, Aguirre S, Pallarés HM, Maestre AM, Sánchez-Vargas I, Blair CD, Fabri C, Morales MA, Fernandez-Sesma A, Gamarnik AV. Filomatori CV, et al. Among authors: aguirre s. PLoS Pathog. 2017 Mar 6;13(3):e1006265. doi: 10.1371/journal.ppat.1006265. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28264033 Free PMC article.
Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS.
Webb LG, Veloz J, Pintado-Silva J, Zhu T, Rangel MV, Mutetwa T, Zhang L, Bernal-Rubio D, Figueroa D, Carrau L, Fenutria R, Potla U, Reid SP, Yount JS, Stapleford KA, Aguirre S, Fernandez-Sesma A. Webb LG, et al. Among authors: aguirre s. PLoS Pathog. 2020 Oct 15;16(10):e1008999. doi: 10.1371/journal.ppat.1008999. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33057424 Free PMC article.
DENV inhibits type I IFN production in infected cells by cleaving human STING.
Aguirre S, Maestre AM, Pagni S, Patel JR, Savage T, Gutman D, Maringer K, Bernal-Rubio D, Shabman RS, Simon V, Rodriguez-Madoz JR, Mulder LC, Barber GN, Fernandez-Sesma A. Aguirre S, et al. PLoS Pathog. 2012;8(10):e1002934. doi: 10.1371/journal.ppat.1002934. Epub 2012 Oct 4. PLoS Pathog. 2012. PMID: 23055924 Free PMC article.
143 results