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A POLD3/BLM dependent pathway handles DSBs in transcribed chromatin upon excessive RNA:DNA hybrid accumulation.
Cohen S, Guenolé A, Lazar I, Marnef A, Clouaire T, Vernekar DV, Puget N, Rocher V, Arnould C, Aguirrebengoa M, Genais M, Firmin N, Shamanna RA, Mourad R, Bohr VA, Borde V, Legube G. Cohen S, et al. Among authors: aguirrebengoa m. Nat Commun. 2022 Apr 19;13(1):2012. doi: 10.1038/s41467-022-29629-2. Nat Commun. 2022. PMID: 35440629 Free PMC article.
Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.
Aymard F, Aguirrebengoa M, Guillou E, Javierre BM, Bugler B, Arnould C, Rocher V, Iacovoni JS, Biernacka A, Skrzypczak M, Ginalski K, Rowicka M, Fraser P, Legube G. Aymard F, et al. Among authors: aguirrebengoa m. Nat Struct Mol Biol. 2017 Apr;24(4):353-361. doi: 10.1038/nsmb.3387. Epub 2017 Mar 6. Nat Struct Mol Biol. 2017. PMID: 28263325 Free PMC article.
24 results