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Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should).
Agustí A. Agustí A. Proc Am Thorac Soc. 2007 Oct 1;4(7):522-5. doi: 10.1513/pats.200701-004FM. Proc Am Thorac Soc. 2007. PMID: 17878464 Review.
This article reviews what is known about it and, more importantly, highlights what is not (but should be) known in order to stimulate research in this area, in the hope that a better understanding of this field may lead to better treatment options for patients with COPD... …
This article reviews what is known about it and, more importantly, highlights what is not (but should be) known in order to stimulate resear …
NF-kappaB activation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight.
Agustí A, Morlá M, Sauleda J, Saus C, Busquets X. Agustí A, et al. Thorax. 2004 Jun;59(6):483-7. doi: 10.1136/thx.2003.017640. Thorax. 2004. PMID: 15170030 Free PMC article.
BACKGROUND: Weight loss, mostly due to skeletal muscle atrophy, is a frequent and clinically relevant problem in patients with chronic obstructive pulmonary disease (COPD). ...RESULTS: Compared with patients with normal body weight, those with low BMI showed a 30% i …
BACKGROUND: Weight loss, mostly due to skeletal muscle atrophy, is a frequent and clinically relevant problem in patients with chroni …
Decreased plasma levels of orexin-A in sleep apnea.
Busquets X, Barbé F, Barceló A, de la Peña M, Sigritz N, Mayoralas LR, Ladaria A, Agustí A. Busquets X, et al. Among authors: agusti a. Respiration. 2004 Nov-Dec;71(6):575-9. doi: 10.1159/000081757. Respiration. 2004. PMID: 15627867
BACKGROUND: Orexin-A, also known as hypocretin, is a neuropeptide implicated in appetite and sleep regulation. Because the obstructive sleep apnea syndrome (OSAS) is characterized by obesity and excessive daytime sleepiness, we hypothesized that orexin-A leve …
BACKGROUND: Orexin-A, also known as hypocretin, is a neuropeptide implicated in appetite and sleep regulation. Because the obs …
[Inhaled steroids in the treatment of COPD].
Cosío BG, Agustí A. Cosío BG, et al. Among authors: agusti a. Rev Clin Esp. 2005 Jan;205(1):24-6. doi: 10.1016/s0014-2565(05)72473-5. Rev Clin Esp. 2005. PMID: 15718014 Spanish. No abstract available.
Proposal for a multidimensional staging system for chronic obstructive pulmonary disease.
Celli BR, Calverley PM, Rennard SI, Wouters EF, Agusti A, Anthonisen N, Macnee W, Jones P, Pride N, Rodriguez-Roisin R, Rossi A, Wanner A. Celli BR, et al. Among authors: agusti a. Respir Med. 2005 Dec;99(12):1546-54. doi: 10.1016/j.rmed.2005.03.019. Respir Med. 2005. PMID: 16291077
We hypothesized that a multidimensional staging system for COPD could provide a more complete assessment of the disease's impact. ...Each measure correlates independently with prognosis in COPD, is supported by a significant body of literature and serves as …
We hypothesized that a multidimensional staging system for COPD could provide a more complete assessment of the disease's impa …
Thomas a. Neff lecture. Chronic obstructive pulmonary disease: a systemic disease.
Agusti A. Agusti A. Proc Am Thorac Soc. 2006 Aug;3(6):478-81. doi: 10.1513/pats.200603-058MS. Proc Am Thorac Soc. 2006. PMID: 16921116 No abstract available.
[Reduced expression of the sarcoplasmic calcium pump SERCA2 in skeletal muscle from patients with chronic obstructive pulmonary disease and low body weight].
Morlà M, Iglesias A, Sauleda J, Cosio B, Agustí A, Busquets X. Morlà M, et al. Among authors: agusti a. Arch Bronconeumol. 2007 Jan;43(1):4-8. doi: 10.1016/s1579-2129(07)60013-5. Arch Bronconeumol. 2007. PMID: 17257557 Spanish.
Finally, a significant negative correlation was observed between the concentration of SERCA2 and that of inducible nitric oxide synthase (determined in a previous study using the same biopsy material) in patients with COPD and low BMI (r=-0.89, P=.007), while such …
Finally, a significant negative correlation was observed between the concentration of SERCA2 and that of inducible nitric oxide synth …
Inflammatory proteins in patients with obstructive sleep apnea with and without daytime sleepiness.
Bravo Mde L, Serpero LD, Barceló A, Barbé F, Agustí A, Gozal D. Bravo Mde L, et al. Among authors: agusti a. Sleep Breath. 2007 Sep;11(3):177-85. doi: 10.1007/s11325-007-0100-7. Sleep Breath. 2007. PMID: 17279423
A total of 50 consecutive patients with OSAS undergoing overnight polysomnography with or without EDS and 20 controls were evaluated. ...
A total of 50 consecutive patients with OSAS undergoing overnight polysomnography with or without EDS and 20 controls were evaluated.
Chronic obstructive pulmonary disease: beyond the forced expiratory manoeuvre.
Agustí A. Agustí A. Respiration. 2008;75(2):136-7. doi: 10.1159/000113612. Epub 2008 Mar 6. Respiration. 2008. PMID: 18332621 No abstract available.
Physical activity and chronic obstructive pulmonary disease.
Agustí A. Agustí A. Am J Respir Crit Care Med. 2008 Apr 1;177(7):675-6. doi: 10.1164/rccm.200712-1790ED. Am J Respir Crit Care Med. 2008. PMID: 18362115 No abstract available.
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