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The transcellular spread of cytosolic amyloids, prions, and prionoids.
Aguzzi A, Rajendran L. Aguzzi A, et al. Neuron. 2009 Dec 24;64(6):783-90. doi: 10.1016/j.neuron.2009.12.016. Neuron. 2009. PMID: 20064386 Review.
Recent reports indicate that a growing number of intracellular proteins are not only prone to pathological aggregation but can also be released and "infect" neighboring cells. Therefore, many complex diseases may obey a simple model of propagation where the penetrat …
Recent reports indicate that a growing number of intracellular proteins are not only prone to pathological aggregation but can also b …
No propagation of prions in mice devoid of PrP.
Sailer A, Büeler H, Fischer M, Aguzzi A, Weissmann C. Sailer A, et al. Cell. 1994 Jul 1;77(7):967-8. doi: 10.1016/0092-8674(94)90436-7. Cell. 1994. PMID: 7912659 No abstract available.
Role of PrP in prion diseases.
Weissmann C, Büeler H, Sailer A, Fischer M, Aguet M, Aguzzi A. Weissmann C, et al. Br Med Bull. 1993 Oct;49(4):995-1011. doi: 10.1093/oxfordjournals.bmb.a072658. Br Med Bull. 1993. PMID: 8137140 Review. No abstract available.
Pathogenesis of spongiform encephalopathies: an update.
Aguzzi A. Aguzzi A. Int Arch Allergy Immunol. 1996 Jun;110(2):99-106. doi: 10.1159/000237273. Int Arch Allergy Immunol. 1996. PMID: 8646000 Review.
Sleepless in Bologna: transmission of fatal familial insomnia.
Aguzzi A, Weissmann C. Aguzzi A, et al. Trends Microbiol. 1996 Apr;4(4):129-31; discussion 131-2. doi: 10.1016/0966-842x(96)30012-7. Trends Microbiol. 1996. PMID: 8728604 Review. No abstract available.
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system.
Brandner S, Raeber A, Sailer A, Blättler T, Fischer M, Weissmann C, Aguzzi A. Brandner S, et al. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13148-51. doi: 10.1073/pnas.93.23.13148. Proc Natl Acad Sci U S A. 1996. PMID: 8917559 Free PMC article.
To determine whether PrPC is required for scrapie spread, we inoculated prions intraocularly into Prnp% mice containing a PrP-overexpressing neurograft. ...
To determine whether PrPC is required for scrapie spread, we inoculated prions intraocularly into Prnp% mice containing a PrP-overexp …
Neuroectodermal grafting: a new tool for the study of neurodegenerative diseases.
Isenmann S, Brandner S, Aguzzi A. Isenmann S, et al. Histol Histopathol. 1996 Oct;11(4):1063-73. Histol Histopathol. 1996. PMID: 8930648 Review.
We have used neural transplantation techniques which allow us to keep CNS tissue of knockout and transgenic mice viable for a prolonged period of time in the brain or in the kidney capsule of healthy recipients. ...
We have used neural transplantation techniques which allow us to keep CNS tissue of knockout and transgenic mice viable for a prolong …
Neuro-immune connection in spread of prions in the body?
Aguzzi A. Aguzzi A. Lancet. 1997 Mar 15;349(9054):742-3. doi: 10.1016/S0140-6736(97)22011-8. Lancet. 1997. PMID: 9074567 No abstract available.
Neurotoxicity and neuroinvasiveness of prions.
Aguzzi A, Raeber A, Blättler T, Flechsig E, Klein M, Weissmann C, Brandner S. Aguzzi A, et al. J Neurovirol. 1997 May;3 Suppl 1:S23-4. J Neurovirol. 1997. PMID: 9179785 No abstract available.
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