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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
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1998 46
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2000 54
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2004 77
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1,829 results

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Page 1
AHR in the intestinal microenvironment: safeguarding barrier function.
Stockinger B, Shah K, Wincent E. Stockinger B, et al. Nat Rev Gastroenterol Hepatol. 2021 Aug;18(8):559-570. doi: 10.1038/s41575-021-00430-8. Epub 2021 Mar 19. Nat Rev Gastroenterol Hepatol. 2021. PMID: 33742166 Free PMC article. Review.
Mammalian aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that belongs to the basic helix-loop-helix (bHLH)-PAS family of transcription factors, which are evolutionarily conserved environmental sensors. ...Upon ligand binding …
Mammalian aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that belongs to the basic h …
The complex biology of aryl hydrocarbon receptor activation in cancer and beyond.
Opitz CA, Holfelder P, Prentzell MT, Trump S. Opitz CA, et al. Biochem Pharmacol. 2023 Oct;216:115798. doi: 10.1016/j.bcp.2023.115798. Epub 2023 Sep 9. Biochem Pharmacol. 2023. PMID: 37696456 Free PMC article. Review.
The aryl hydrocarbon receptor (AHR) signaling pathway is a complex regulatory network that plays a critical role in various biological processes, including cellular metabolism, development, and immune responses. The complexity of AHR signaling a …
The aryl hydrocarbon receptor (AHR) signaling pathway is a complex regulatory network that plays a critical role …
Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway.
Sondermann NC, Faßbender S, Hartung F, Hätälä AM, Rolfes KM, Vogel CFA, Haarmann-Stemmann T. Sondermann NC, et al. Biochem Pharmacol. 2023 Feb;208:115371. doi: 10.1016/j.bcp.2022.115371. Epub 2022 Dec 15. Biochem Pharmacol. 2023. PMID: 36528068 Free PMC article. Review.
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating adaptive and maladaptive responses toward exogenous and endogenous signals. ...However, the ligand-based targeting of AHR is considerably complicated by th …
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating adaptive and maladapti …
Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex.
Diao X, Shang Q, Guo M, Huang Y, Zhang M, Chen X, Liang Y, Sun X, Zhou F, Zhuang J, Liu SJ, Vogel CFA, Rastinejad F, Wu D. Diao X, et al. Nat Commun. 2025 Feb 3;16(1):1282. doi: 10.1038/s41467-025-56574-7. Nat Commun. 2025. PMID: 39900897 Free PMC article.
The aryl hydrocarbon receptor (AHR) possesses an extraordinary capacity to sense and respond to a wide range of small-molecule ligands, ranging from polycyclic aromatic hydrocarbons to endogenous compounds. Upon ligand binding, AHR translocates …
The aryl hydrocarbon receptor (AHR) possesses an extraordinary capacity to sense and respond to a wide range of …
Benvitimod Inhibits IL-4- and IL-13-Induced Tight Junction Impairment by Activating AHR/ARNT Pathway and Inhibiting STAT6 Phosphorylation in Human Keratinocytes.
Wang X, Mao D, Jia J, Zhang J. Wang X, et al. J Invest Dermatol. 2024 Mar;144(3):509-519.e7. doi: 10.1016/j.jid.2023.07.027. Epub 2023 Sep 20. J Invest Dermatol. 2024. PMID: 37734479 Free article.
Benvitimod, a new drug for atopic dermatitis, upregulated CLDN4 and OCLN through the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator pathway. Benvitimod induced nuclear translocation of NRF2 a …
Benvitimod, a new drug for atopic dermatitis, upregulated CLDN4 and OCLN through the aryl hydrocarbon receptor/aryl …
Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator.
Evans BR, Karchner SI, Allan LL, Pollenz RS, Tanguay RL, Jenny MJ, Sherr DH, Hahn ME. Evans BR, et al. Mol Pharmacol. 2008 Feb;73(2):387-98. doi: 10.1124/mol.107.040204. Epub 2007 Nov 13. Mol Pharmacol. 2008. PMID: 18000031 Free PMC article.
Activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin causes altered gene expression and toxicity. The AHR repressor (AHRR) inhibits AHR signaling through a proposed mechanism involving competition with …
Activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin causes altered gene exp …
The aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT) heterodimer interacts with naturally occurring estrogen response elements.
Klinge CM, Bowers JL, Kulakosky PC, Kamboj KK, Swanson HI. Klinge CM, et al. Mol Cell Endocrinol. 1999 Nov 25;157(1-2):105-19. doi: 10.1016/s0303-7207(99)00165-3. Mol Cell Endocrinol. 1999. PMID: 10619402
To determine the molecular mechanisms underlying the "cross talk" between the activity of 2,3,7,8-tetra-chlorodibenzo-p-dioxin (TCDD), which binds to arylhydrocarbon receptor (AHR) and estradiol (E2)-liganded estrogen receptor (ER), we first examined the init …
To determine the molecular mechanisms underlying the "cross talk" between the activity of 2,3,7,8-tetra-chlorodibenzo-p-dioxin (TCDD), which …
Coactivator recruitment of AhR/ARNT1.
Endler A, Chen L, Shibasaki F. Endler A, et al. Int J Mol Sci. 2014 Jun 19;15(6):11100-10. doi: 10.3390/ijms150611100. Int J Mol Sci. 2014. PMID: 24950180 Free PMC article. Review.
In this review, we focus on our recent findings related to the recruitment of steroid receptor coactivator 1 (SRC1/NCoA1) by the estrogen receptor-alpha (ERalpha) and by the arylhydrocarbon receptor/arylhydrocarbon receptor nuclear translocat …
In this review, we focus on our recent findings related to the recruitment of steroid receptor coactivator 1 (SRC1/NCoA1) by the estr …
Expression of the aryl hydrocarbon receptor (AhR) and the aryl hydrocarbon receptor nuclear translocator (ARNT) in fetal, benign hyperplastic, and malignant prostate.
Kashani M, Steiner G, Haitel A, Schaufler K, Thalhammer T, Amann G, Kramer G, Marberger M, Schöller A. Kashani M, et al. Prostate. 1998 Oct 1;37(2):98-108. doi: 10.1002/(sici)1097-0045(19981001)37:2<98::aid-pros6>3.0.co;2-h. Prostate. 1998. PMID: 9759704
BACKGROUND: Androgen-dependent tissue has been reported to be affected by chemical ligands of the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, which heterodimerizes with the aryl hydrocarbon receptor …
BACKGROUND: Androgen-dependent tissue has been reported to be affected by chemical ligands of the aryl hydrocarbon receptor …
Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels.
Kim EY, Iwata H, Suda T, Tanabe S, Amano M, Miyazaki N, Petrov EA. Kim EY, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Jul;141(3):281-91. doi: 10.1016/j.cca.2005.07.007. Comp Biochem Physiol C Toxicol Pharmacol. 2005. PMID: 16111922
Most toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related planar halogenated aromatic hydrocarbons (PHAHs) are mediated by ligand-activated aryl hydrocarbon receptor (AHR) signaling pathway. To understand the regulation mechanism of …
Most toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related planar halogenated aromatic hydrocarbons (PHAHs) are mediated b …
1,829 results