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2,131 results
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Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway.
Grakoui A, John Wherry E, Hanson HL, Walker C, Ahmed R. Grakoui A, et al. Among authors: ahmed r. J Hepatol. 2006 Oct;45(4):468-72. doi: 10.1016/j.jhep.2006.07.009. Epub 2006 Jul 25. J Hepatol. 2006. PMID: 16901572 Review. No abstract available.
PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.
Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R. Mueller SN, et al. Among authors: ahmed r. J Clin Invest. 2010 Jul;120(7):2508-15. doi: 10.1172/JCI40040. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551512 Free PMC article.
Unraveling the role of PD-1/PD-L interactions in persistent hepatotropic infections: potential for therapeutic application?
Radziewicz H, Hanson HL, Ahmed R, Grakoui A. Radziewicz H, et al. Among authors: ahmed r. Gastroenterology. 2008 Jun;134(7):2168-71. doi: 10.1053/j.gastro.2008.04.012. Epub 2008 May 16. Gastroenterology. 2008. PMID: 18486616 No abstract available.
Role of PD-1 in regulating T-cell immunity.
Jin HT, Ahmed R, Okazaki T. Jin HT, et al. Among authors: ahmed r. Curr Top Microbiol Immunol. 2011;350:17-37. doi: 10.1007/82_2010_116. Curr Top Microbiol Immunol. 2011. PMID: 21061197 Review.
PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.
West EE, Jin HT, Rasheed AU, Penaloza-Macmaster P, Ha SJ, Tan WG, Youngblood B, Freeman GJ, Smith KA, Ahmed R. West EE, et al. Among authors: ahmed r. J Clin Invest. 2013 Jun;123(6):2604-15. doi: 10.1172/JCI67008. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676462 Free PMC article.
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.
Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Radziewicz H, et al. Among authors: ahmed r. J Virol. 2007 Mar;81(6):2545-53. doi: 10.1128/JVI.02021-06. Epub 2006 Dec 20. J Virol. 2007. PMID: 17182670 Free PMC article.
4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection.
Vezys V, Penaloza-MacMaster P, Barber DL, Ha SJ, Konieczny B, Freeman GJ, Mittler RS, Ahmed R. Vezys V, et al. Among authors: ahmed r. J Immunol. 2011 Aug 15;187(4):1634-42. doi: 10.4049/jimmunol.1100077. Epub 2011 Jul 8. J Immunol. 2011. PMID: 21742975 Free PMC article.
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.
Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Freeman GJ, et al. Among authors: ahmed r. J Exp Med. 2006 Oct 2;203(10):2223-7. doi: 10.1084/jem.20061800. Epub 2006 Sep 25. J Exp Med. 2006. PMID: 17000870 Free PMC article. Review.
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. Day CL, et al. Among authors: ahmed r. Nature. 2006 Sep 21;443(7109):350-4. doi: 10.1038/nature05115. Epub 2006 Aug 20. Nature. 2006. PMID: 16921384
Dynamic regulation of T cell immunity by CD43.
Onami TM, Harrington LE, Williams MA, Galvan M, Larsen CP, Pearson TC, Manjunath N, Baum LG, Pearce BD, Ahmed R. Onami TM, et al. Among authors: ahmed r. J Immunol. 2002 Jun 15;168(12):6022-31. doi: 10.4049/jimmunol.168.12.6022. J Immunol. 2002. PMID: 12055210
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