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Electrophilic tuning of the chemoprotective natural product sulforaphane.
Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA. Ahn YH, et al. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9590-5. doi: 10.1073/pnas.1004104107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439747 Free PMC article.
Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition.
Dancy BM, Crump NT, Peterson DJ, Mukherjee C, Bowers EM, Ahn YH, Yoshida M, Zhang J, Mahadevan LC, Meyers DJ, Boeke JD, Cole PA. Dancy BM, et al. Among authors: ahn yh. Chembiochem. 2012 Sep 24;13(14):2113-21. doi: 10.1002/cbic.201200381. Epub 2012 Sep 7. Chembiochem. 2012. PMID: 22961914 Free PMC article.
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
Chiang MJ, Holbert MA, Kalin JH, Ahn YH, Giddens J, Amin MN, Taylor MS, Collins SL, Chan-Li Y, Waickman A, Hsiao PY, Bolduc D, Leahy DJ, Horton MR, Wang LX, Powell JD, Cole PA. Chiang MJ, et al. Among authors: ahn yh. J Am Chem Soc. 2014 Mar 5;136(9):3370-3. doi: 10.1021/ja5006674. Epub 2014 Feb 24. J Am Chem Soc. 2014. PMID: 24533830 Free PMC article.
YcgC represents a new protein deacetylase family in prokaryotes.
Tu S, Guo SJ, Chen CS, Liu CX, Jiang HW, Ge F, Deng JY, Zhou YM, Czajkowsky DM, Li Y, Qi BR, Ahn YH, Cole PA, Zhu H, Tao SC. Tu S, et al. Among authors: ahn yh. Elife. 2015 Dec 30;4:e05322. doi: 10.7554/eLife.05322. Elife. 2015. PMID: 26716769 Free PMC article.
Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease.
Ahuja M, Ammal Kaidery N, Attucks OC, McDade E, Hushpulian DM, Gaisin A, Gaisina I, Ahn YH, Nikulin S, Poloznikov A, Gazaryan I, Yamamoto M, Matsumoto M, Igarashi K, Sharma SM, Thomas B. Ahuja M, et al. Among authors: ahn yh. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2111643118. doi: 10.1073/pnas.2111643118. Proc Natl Acad Sci U S A. 2021. PMID: 34737234 Free PMC article.
635 results