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Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain.
Aiken C, Konner J, Landau NR, Lenburg ME, Trono D. Aiken C, et al. Cell. 1994 Mar 11;76(5):853-64. doi: 10.1016/0092-8674(94)90360-3. Cell. 1994. PMID: 8124721
Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.
Lundquist CA, Zhou J, Aiken C. Lundquist CA, et al. Among authors: aiken c. J Virol. 2004 Jun;78(12):6287-96. doi: 10.1128/JVI.78.12.6287-6296.2004. J Virol. 2004. PMID: 15163722 Free PMC article.
Nef does not affect the efficiency of human immunodeficiency virus type 1 fusion with target cells.
Tobiume M, Lineberger JE, Lundquist CA, Miller MD, Aiken C. Tobiume M, et al. Among authors: aiken c. J Virol. 2003 Oct;77(19):10645-50. doi: 10.1128/jvi.77.19.10645-10650.2003. J Virol. 2003. PMID: 12970449 Free PMC article.
Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.
Lundquist CA, Tobiume M, Zhou J, Unutmaz D, Aiken C. Lundquist CA, et al. Among authors: aiken c. J Virol. 2002 May;76(9):4625-33. doi: 10.1128/jvi.76.9.4625-4633.2002. J Virol. 2002. PMID: 11932428 Free PMC article.
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane.
Mangasarian A, Foti M, Aiken C, Chin D, Carpentier JL, Trono D. Mangasarian A, et al. Among authors: aiken c. Immunity. 1997 Jan;6(1):67-77. doi: 10.1016/s1074-7613(00)80243-5. Immunity. 1997. PMID: 9052838
Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation.
Aiken C, Krause L, Chen YL, Trono D. Aiken C, et al. Virology. 1996 Mar 1;217(1):293-300. doi: 10.1006/viro.1996.0116. Virology. 1996. PMID: 8599214
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells.
von Schwedler U, Song J, Aiken C, Trono D. von Schwedler U, et al. Among authors: aiken c. J Virol. 1993 Aug;67(8):4945-55. doi: 10.1128/JVI.67.8.4945-4955.1993. J Virol. 1993. PMID: 8331734 Free PMC article.
HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator.
Gallay P, Swingler S, Aiken C, Trono D. Gallay P, et al. Among authors: aiken c. Cell. 1995 Feb 10;80(3):379-88. doi: 10.1016/0092-8674(95)90488-3. Cell. 1995. PMID: 7859280
During virus assembly, a subset of MA is phosphorylated on the C-terminal tyrosine by a virion-associated cellular protein kinase. ...
During virus assembly, a subset of MA is phosphorylated on the C-terminal tyrosine by a virion-associated cellular protein kinase. .. …
Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis.
Aiken C, Trono D. Aiken C, et al. J Virol. 1995 Aug;69(8):5048-56. doi: 10.1128/JVI.69.8.5048-5056.1995. J Virol. 1995. PMID: 7541845 Free PMC article.
Differential effects of human cytomegalovirus on integrated and unintegrated human immunodeficiency virus sequences.
Koval V, Jault FM, Pal PG, Moreno TN, Aiken C, Trono D, Spector SA, Spector DH. Koval V, et al. Among authors: aiken c. J Virol. 1995 Mar;69(3):1645-51. doi: 10.1128/JVI.69.3.1645-1651.1995. J Virol. 1995. PMID: 7853500 Free PMC article.
Koval, C. Clark, M. Vaishnav, S. A. Spector, and D. H. Spector, J. Virol. 65:6969-6978, 1991). We show here that HCMV can also activate an infectious proviral HIV-1 genome transiently transfected into a cell. ...
Koval, C. Clark, M. Vaishnav, S. A. Spector, and D. H. Spector, J. Virol. 65:6969-6978, 1991). We show here that HCMV can also activa …
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