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MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.
Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, Farzan F, Leri F, MacQueen GM, Feilotter H, Tyryshkin K, Evans KR, Giacobbe P, Blier P, Lam RW, Milev R, Parikh SV, Rotzinger S, Strother SC, Lewis CM, Aitchison KJ, Wittenberg GM, Mechawar N, Nestler EJ, Uher R, Kennedy SH, Turecki G. Lopez JP, et al. Among authors: aitchison kj. Nat Commun. 2017 May 22;8:15497. doi: 10.1038/ncomms15497. Nat Commun. 2017. PMID: 28530238 Free PMC article. Clinical Trial.
Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.
Iniesta R, Hodgson K, Stahl D, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Dobson R, Aitchison KJ, Farmer A, McGuffin P, Lewis CM, Uher R. Iniesta R, et al. Among authors: aitchison kj. Sci Rep. 2018 Apr 3;8(1):5530. doi: 10.1038/s41598-018-23584-z. Sci Rep. 2018. PMID: 29615645 Free PMC article. Clinical Trial.
Investigation of blood mRNA biomarkers for suicidality in an independent sample.
Mullins N, Hodgson K, Tansey KE, Perroud N, Maier W, Mors O, Rietschel M, Hauser J, Henigsberg N, Souery D, Aitchison K, Farmer A, McGuffin P, Breen G, Uher R, Lewis CM. Mullins N, et al. Transl Psychiatry. 2014 Oct 28;4(10):e474. doi: 10.1038/tp.2014.112. Transl Psychiatry. 2014. PMID: 25350297 Free PMC article.
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.
Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM, Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I, Lewis CM, McGuffin P. Uher R, et al. Among authors: aitchison kj. Am J Psychiatry. 2010 May;167(5):555-64. doi: 10.1176/appi.ajp.2009.09070932. Epub 2010 Apr 1. Am J Psychiatry. 2010. PMID: 20360315
Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.
Tansey KE, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans D, Hall SK, Hauser J, Henigsberg N, Hu X, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Holmans P, Lewis G, Lewis CM, Stensbøl TB, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Among authors: aitchison kj. PLoS Med. 2012;9(10):e1001326. doi: 10.1371/journal.pmed.1001326. Epub 2012 Oct 16. PLoS Med. 2012. PMID: 23091423 Free PMC article.
Combining clinical variables to optimize prediction of antidepressant treatment outcomes.
Iniesta R, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Stahl D, Dobson R, Aitchison KJ, Farmer A, Lewis CM, McGuffin P, Uher R. Iniesta R, et al. Among authors: aitchison kj. J Psychiatr Res. 2016 Jul;78:94-102. doi: 10.1016/j.jpsychires.2016.03.016. Epub 2016 Apr 1. J Psychiatr Res. 2016. PMID: 27089522 Free article. Clinical Trial.
Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP).
Ren H, Fabbri C, Uher R, Rietschel M, Mors O, Henigsberg N, Hauser J, Zobel A, Maier W, Dernovsek MZ, Souery D, Cattaneo A, Breen G, Craig IW, Farmer AE, McGuffin P, Lewis CM, Aitchison KJ. Ren H, et al. Among authors: aitchison kj. Transl Psychiatry. 2018 Aug 13;8(1):150. doi: 10.1038/s41398-018-0198-3. Transl Psychiatry. 2018. PMID: 30104601 Free PMC article.
Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.
Perroud N, Aitchison KJ, Uher R, Smith R, Huezo-Diaz P, Marusic A, Maier W, Mors O, Placentino A, Henigsberg N, Rietschel M, Hauser J, Souery D, Kapelski P, Bonvicini C, Zobel A, Jorgensen L, Petrovic A, Kalember P, Schulze TG, Gupta B, Gray J, Lewis CM, Farmer AE, McGuffin P, Craig I. Perroud N, et al. Among authors: aitchison kj. Neuropsychopharmacology. 2009 Nov;34(12):2517-28. doi: 10.1038/npp.2009.81. Epub 2009 Jul 29. Neuropsychopharmacology. 2009. PMID: 19641488 Clinical Trial.
160 results