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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium; Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J. Menden MP, et al. Nat Commun. 2019 Jun 17;10(1):2674. doi: 10.1038/s41467-019-09799-2. Nat Commun. 2019. PMID: 31209238 Free PMC article.
Regularized machine learning in the genetic prediction of complex traits.
Okser S, Pahikkala T, Airola A, Salakoski T, Ripatti S, Aittokallio T. Okser S, et al. Among authors: aittokallio t. PLoS Genet. 2014 Nov 13;10(11):e1004754. doi: 10.1371/journal.pgen.1004754. eCollection 2014 Nov. PLoS Genet. 2014. PMID: 25393026 Free PMC article. No abstract available.
Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer.
He L, Bulanova D, Oikkonen J, Häkkinen A, Zhang K, Zheng S, Wang W, Erkan EP, Carpén O, Joutsiniemi T, Hietanen S, Hynninen J, Huhtinen K, Hautaniemi S, Vähärautio A, Tang J, Wennerberg K, Aittokallio T. He L, et al. Among authors: aittokallio t. Brief Bioinform. 2021 Nov 5;22(6):bbab272. doi: 10.1093/bib/bbab272. Brief Bioinform. 2021. PMID: 34343245 Free PMC article.
Systematic review of computational methods for drug combination prediction.
Kong W, Midena G, Chen Y, Athanasiadis P, Wang T, Rousu J, He L, Aittokallio T. Kong W, et al. Among authors: aittokallio t. Comput Struct Biotechnol J. 2022 Jun 1;20:2807-2814. doi: 10.1016/j.csbj.2022.05.055. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35685365 Free PMC article. Review.
253 results