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New insights into the pathogenesis of adenosine deaminase-severe combined immunodeficiency and progress in gene therapy.
Sauer AV, Aiuti A. Sauer AV, et al. Among authors: aiuti a. Curr Opin Allergy Clin Immunol. 2009 Dec;9(6):496-502. doi: 10.1097/ACI.0b013e3283327da5. Curr Opin Allergy Clin Immunol. 2009. PMID: 19779332 Review.
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer.
Ruggieri L, Aiuti A, Salomoni M, Zappone E, Ferrari G, Bordignon C. Ruggieri L, et al. Among authors: aiuti a. Hum Gene Ther. 1997 Sep 1;8(13):1611-23. doi: 10.1089/hum.1997.8.13-1611. Hum Gene Ther. 1997. PMID: 9322094
Transcriptional targeting of retroviral vectors to the erythroblastic progeny of transduced hematopoietic stem cells.
Grande A, Piovani B, Aiuti A, Ottolenghi S, Mavilio F, Ferrari G. Grande A, et al. Among authors: aiuti a. Blood. 1999 May 15;93(10):3276-85. Blood. 1999. PMID: 10233879
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors.
Aiuti A, Tavian M, Cipponi A, Ficara F, Zappone E, Hoxie J, Peault B, Bordignon C. Aiuti A, et al. Eur J Immunol. 1999 Jun;29(6):1823-31. doi: 10.1002/(SICI)1521-4141(199906)29:06<1823::AID-IMMU1823>3.0.CO;2-B. Eur J Immunol. 1999. PMID: 10382744
Optimisation of retroviral supernatant production conditions for the genetic modification of human CD34+ cells.
Dando JS, Aiuti A, Deola S, Ficara F, Bordignon C. Dando JS, et al. Among authors: aiuti a. J Gene Med. 2001 May-Jun;3(3):219-27. doi: 10.1002/1521-2254(200105/06)3:3<219::AID-JGM184>3.0.CO;2-E. J Gene Med. 2001. PMID: 11437327
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors.
Dando JS, Roncarolo MG, Bordignon C, Aiuti A. Dando JS, et al. Among authors: aiuti a. Hum Gene Ther. 2001 Nov 1;12(16):1979-88. doi: 10.1089/104303401753204553. Hum Gene Ther. 2001. PMID: 11686939
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning.
Aiuti A, Slavin S, Aker M, Ficara F, Deola S, Mortellaro A, Morecki S, Andolfi G, Tabucchi A, Carlucci F, Marinello E, Cattaneo F, Vai S, Servida P, Miniero R, Roncarolo MG, Bordignon C. Aiuti A, et al. Science. 2002 Jun 28;296(5577):2410-3. doi: 10.1126/science.1070104. Science. 2002. PMID: 12089448 Clinical Trial.
Assessment of thymic output in common variable immunodeficiency patients by evaluation of T cell receptor excision circles.
Guazzi V, Aiuti F, Mezzaroma I, Mazzetta F, Andolfi G, Mortellaro A, Pierdominici M, Fantini R, Marziali M, Aiuti A. Guazzi V, et al. Among authors: aiuti f, aiuti a. Clin Exp Immunol. 2002 Aug;129(2):346-53. doi: 10.1046/j.1365-2249.2002.01893.x. Clin Exp Immunol. 2002. PMID: 12165093 Free PMC article.
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.
Dupré L, Aiuti A, Trifari S, Martino S, Saracco P, Bordignon C, Roncarolo MG. Dupré L, et al. Among authors: aiuti a. Immunity. 2002 Aug;17(2):157-66. doi: 10.1016/s1074-7613(02)00360-6. Immunity. 2002. PMID: 12196287
Advances in gene therapy for ADA-deficient SCID.
Aiuti A. Aiuti A. Curr Opin Mol Ther. 2002 Oct;4(5):515-22. Curr Opin Mol Ther. 2002. PMID: 12435054 Review.
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