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Hypoxic induction of Ctgf is directly mediated by Hif-1.
Higgins DF, Biju MP, Akai Y, Wutz A, Johnson RS, Haase VH. Higgins DF, et al. Among authors: akai y. Am J Physiol Renal Physiol. 2004 Dec;287(6):F1223-32. doi: 10.1152/ajprenal.00245.2004. Epub 2004 Aug 17. Am J Physiol Renal Physiol. 2004. PMID: 15315937 Free article.
Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.
Kimura K, Iwano M, Higgins DF, Yamaguchi Y, Nakatani K, Harada K, Kubo A, Akai Y, Rankin EB, Neilson EG, Haase VH, Saito Y. Kimura K, et al. Among authors: akai y. Am J Physiol Renal Physiol. 2008 Oct;295(4):F1023-9. doi: 10.1152/ajprenal.90209.2008. Epub 2008 Jul 30. Am J Physiol Renal Physiol. 2008. PMID: 18667485 Free PMC article.
Urinary FSP1 is a biomarker of crescentic GN.
Iwano M, Yamaguchi Y, Iwamoto T, Nakatani K, Matsui M, Kubo A, Akai Y, Mori T, Saito Y. Iwano M, et al. Among authors: akai y. J Am Soc Nephrol. 2012 Feb;23(2):209-14. doi: 10.1681/ASN.2011030229. Epub 2011 Nov 17. J Am Soc Nephrol. 2012. PMID: 22095943 Free PMC article.
161 results