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Synthesis of monoesters of pyrroloquinoline quinone and imidazopyrroloquinoline, and radical scavenging activities using electron spin resonance in vitro and pharmacological activity in vivo.
Urakami T, Yoshida C, Akaike T, Maeda H, Nishigori H, Niki E. Urakami T, et al. Among authors: akaike t. J Nutr Sci Vitaminol (Tokyo). 1997 Feb;43(1):19-33. doi: 10.3177/jnsv.43.19. J Nutr Sci Vitaminol (Tokyo). 1997. PMID: 9151238
Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner.
Yasuhara R, Miyamoto Y, Akaike T, Akuta T, Nakamura M, Takami M, Morimura N, Yasu K, Kamijo R. Yasuhara R, et al. Among authors: akaike t. Biochem J. 2005 Jul 15;389(Pt 2):315-23. doi: 10.1042/BJ20041996. Biochem J. 2005. PMID: 15784009 Free PMC article.
The protective effect of pyrroloquinoline quinone and its derivatives against carbon tetrachloride-induced liver injury of rats.
Tsuchida T, Yasuyama T, Higuchi K, Watanabe A, Urakami T, Akaike T, Sato K, Maeda H. Tsuchida T, et al. Among authors: akaike t. J Gastroenterol Hepatol. 1993 Jul-Aug;8(4):342-7. doi: 10.1111/j.1440-1746.1993.tb01525.x. J Gastroenterol Hepatol. 1993. PMID: 8397011
Superoxide scavenging activity of erythromycin-iron complex.
Muranaka H, Suga M, Sato K, Nakagawa K, Akaike T, Okamoto T, Maeda H, Ando M. Muranaka H, et al. Among authors: akaike t. Biochem Biophys Res Commun. 1997 Mar 6;232(1):183-7. doi: 10.1006/bbrc.1997.6182. Biochem Biophys Res Commun. 1997. PMID: 9125127
Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: implications for the anti-tumor-promoter effect of vegetables.
Sawa T, Nakao M, Akaike T, Ono K, Maeda H. Sawa T, et al. Among authors: akaike t. J Agric Food Chem. 1999 Feb;47(2):397-402. doi: 10.1021/jf980765e. J Agric Food Chem. 1999. PMID: 10563906
Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals.
Akaike T, Noguchi Y, Ijiri S, Setoguchi K, Suga M, Zheng YM, Dietzschold B, Maeda H. Akaike T, et al. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2448-53. doi: 10.1073/pnas.93.6.2448. Proc Natl Acad Sci U S A. 1996. PMID: 8637894 Free PMC article.
Oxygen free radicals as pathogenic molecules in viral diseases.
Maeda H, Akaike T. Maeda H, et al. Among authors: akaike t. Proc Soc Exp Biol Med. 1991 Nov;198(2):721-7. doi: 10.3181/00379727-198-43309c. Proc Soc Exp Biol Med. 1991. PMID: 1656471 Review.
Hydroxyl radical production by H2O2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from the oxidatively damaged enzyme.
Sato K, Akaike T, Kohno M, Ando M, Maeda H. Sato K, et al. Among authors: akaike t. J Biol Chem. 1992 Dec 15;267(35):25371-7. J Biol Chem. 1992. PMID: 1334093
Generation of free radicals from neocarzinostatin mediated by NADPH/cytochrome P-450 reductase via activation of enediyne chromophore.
Sato K, Akaike T, Suga M, Ando M, Maeda H. Sato K, et al. Among authors: akaike t. Biochem Biophys Res Commun. 1994 Dec 30;205(3):1716-23. doi: 10.1006/bbrc.1994.2866. Biochem Biophys Res Commun. 1994. PMID: 7811256
Development of a fluorescent indicator for the bioimaging of nitric oxide.
Kojima H, Sakurai K, Kikuchi K, Kawahara S, Kirino Y, Nagoshi H, Hirata Y, Akaike T, Maeda H, Nagano T. Kojima H, et al. Among authors: akaike t. Biol Pharm Bull. 1997 Dec;20(12):1229-32. doi: 10.1248/bpb.20.1229. Biol Pharm Bull. 1997. PMID: 9448093
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