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Page 1
ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome.
Liiv M, Vaarmann A, Safiulina D, Choubey V, Gupta R, Kuum M, Janickova L, Hodurova Z, Cagalinec M, Zeb A, Hickey MA, Huang YL, Gogichaishvili N, Mandel M, Plaas M, Vasar E, Loncke J, Vervliet T, Tsai TF, Bultynck G, Veksler V, Kaasik A. Liiv M, et al. Among authors: zeb a. Nat Commun. 2024 Jul 21;15(1):6143. doi: 10.1038/s41467-024-50502-x. Nat Commun. 2024. PMID: 39034309 Free PMC article.
Mitochondrial biogenesis is required for axonal growth.
Vaarmann A, Mandel M, Zeb A, Wareski P, Liiv J, Kuum M, Antsov E, Liiv M, Cagalinec M, Choubey V, Kaasik A. Vaarmann A, et al. Among authors: zeb a. Development. 2016 Jun 1;143(11):1981-92. doi: 10.1242/dev.128926. Epub 2016 Apr 27. Development. 2016. PMID: 27122166
Miro proteins prime mitochondria for Parkin translocation and mitophagy.
Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey MA, Cagalinec M, Mandel M, Zeb A, Liiv M, Kaasik A. Safiulina D, et al. Among authors: zeb a. EMBO J. 2019 Jan 15;38(2):e99384. doi: 10.15252/embj.201899384. Epub 2018 Nov 30. EMBO J. 2019. PMID: 30504269 Free PMC article.
A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy.
Zeb A, Choubey V, Gupta R, Kuum M, Safiulina D, Vaarmann A, Gogichaishvili N, Liiv M, Ilves I, Tämm K, Veksler V, Kaasik A. Zeb A, et al. Redox Biol. 2021 Dec;48:102186. doi: 10.1016/j.redox.2021.102186. Epub 2021 Nov 11. Redox Biol. 2021. PMID: 34801863 Free PMC article.
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
Sanz A, Soikkeli M, Portero-Otín M, Wilson A, Kemppainen E, McIlroy G, Ellilä S, Kemppainen KK, Tuomela T, Lakanmaa M, Kiviranta E, Stefanatos R, Dufour E, Hutz B, Naudí A, Jové M, Zeb A, Vartiainen S, Matsuno-Yagi A, Yagi T, Rustin P, Pamplona R, Jacobs HT. Sanz A, et al. Among authors: zeb a. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9105-10. doi: 10.1073/pnas.0911539107. Epub 2010 Apr 30. Proc Natl Acad Sci U S A. 2010. PMID: 20435911 Free PMC article.