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BIOSAFETY. Safeguarding gene drive experiments in the laboratory.
Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J. Akbari OS, et al. Science. 2015 Aug 28;349(6251):927-9. doi: 10.1126/science.aac7932. Epub 2015 Jul 30. Science. 2015. PMID: 26229113 Free PMC article. No abstract available.
Rules of the road for insect gene drive research and testing.
Adelman Z, Akbari O, Bauer J, Bier E, Bloss C, Carter SR, Callender C, Denis AC, Cowhey P, Dass B, Delborne J, Devereaux M, Ellsworth P, Friedman RM, Gantz V, Gibson C, Hay BA, Hoddle M, James AA, James S, Jorgenson L, Kalichman M, Marshall J, McGinnis W, Newman J, Pearson A, Quemada H, Rudenko L, Shelton A, Vinetz JM, Weisman J, Wong B, Wozniak C. Adelman Z, et al. Nat Biotechnol. 2017 Aug 8;35(8):716-718. doi: 10.1038/nbt.3926. Nat Biotechnol. 2017. PMID: 28787415 Free PMC article. No abstract available.
Gene editing technologies and applications for insects.
Gantz VM, Akbari OS. Gantz VM, et al. Among authors: akbari os. Curr Opin Insect Sci. 2018 Aug;28:66-72. doi: 10.1016/j.cois.2018.05.006. Epub 2018 May 22. Curr Opin Insect Sci. 2018. PMID: 30551769 Free PMC article. Review.
Active Genetic Neutralizing Elements for Halting or Deleting Gene Drives.
Xu XS, Bulger EA, Gantz VM, Klanseck C, Heimler SR, Auradkar A, Bennett JB, Miller LA, Leahy S, Juste SS, Buchman A, Akbari OS, Marshall JM, Bier E. Xu XS, et al. Among authors: akbari os. Mol Cell. 2020 Oct 15;80(2):246-262.e4. doi: 10.1016/j.molcel.2020.09.003. Epub 2020 Sep 18. Mol Cell. 2020. PMID: 32949493 Free PMC article.
Core commitments for field trials of gene drive organisms.
Long KC, Alphey L, Annas GJ, Bloss CS, Campbell KJ, Champer J, Chen CH, Choudhary A, Church GM, Collins JP, Cooper KL, Delborne JA, Edwards OR, Emerson CI, Esvelt K, Evans SW, Friedman RM, Gantz VM, Gould F, Hartley S, Heitman E, Hemingway J, Kanuka H, Kuzma J, Lavery JV, Lee Y, Lorenzen M, Lunshof JE, Marshall JM, Messer PW, Montell C, Oye KA, Palmer MJ, Papathanos PA, Paradkar PN, Piaggio AJ, Rasgon JL, Rašić G, Rudenko L, Saah JR, Scott MJ, Sutton JT, Vorsino AE, Akbari OS. Long KC, et al. Among authors: akbari os. Science. 2020 Dec 18;370(6523):1417-1419. doi: 10.1126/science.abd1908. Science. 2020. PMID: 33335055 No abstract available.
Inherently confinable split-drive systems in Drosophila.
Terradas G, Buchman AB, Bennett JB, Shriner I, Marshall JM, Akbari OS, Bier E. Terradas G, et al. Among authors: akbari os. Nat Commun. 2021 Mar 5;12(1):1480. doi: 10.1038/s41467-021-21771-7. Nat Commun. 2021. PMID: 33674604 Free PMC article.
CRISPR mediated transactivation in the human disease vector Aedes aegypti.
Bui M, Dalla Benetta E, Dong Y, Zhao Y, Yang T, Li M, Antoshechkin IA, Buchman A, Bottino-Rojas V, James AA, Perry MW, Dimopoulos G, Akbari OS. Bui M, et al. Among authors: akbari os. PLoS Pathog. 2023 Jan 19;19(1):e1010842. doi: 10.1371/journal.ppat.1010842. eCollection 2023 Jan. PLoS Pathog. 2023. PMID: 36656895 Free PMC article.
128 results