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Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.
Abdulrahman BA, Khweek AA, Akhter A, Caution K, Kotrange S, Abdelaziz DH, Newland C, Rosales-Reyes R, Kopp B, McCoy K, Montione R, Schlesinger LS, Gavrilin MA, Wewers MD, Valvano MA, Amer AO. Abdulrahman BA, et al. Among authors: akhter a. Autophagy. 2011 Nov;7(11):1359-70. doi: 10.4161/auto.7.11.17660. Epub 2011 Nov 1. Autophagy. 2011. PMID: 21997369 Free PMC article.
Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.
Abdelaziz DH, Gavrilin MA, Akhter A, Caution K, Kotrange S, Khweek AA, Abdulrahman BA, Hassan ZA, El-Sharkawi FZ, Bedi SS, Ladner K, Gonzalez-Mejia ME, Doseff AI, Mostafa M, Kanneganti TD, Guttridge D, Marsh CB, Wewers MD, Amer AO. Abdelaziz DH, et al. Among authors: akhter a. Front Microbiol. 2011 Feb 14;2:18. doi: 10.3389/fmicb.2011.00018. eCollection 2011. Front Microbiol. 2011. PMID: 21713115 Free PMC article.
Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia.
Gavrilin MA, Abdelaziz DH, Mostafa M, Abdulrahman BA, Grandhi J, Akhter A, Abu Khweek A, Aubert DF, Valvano MA, Wewers MD, Amer AO. Gavrilin MA, et al. Among authors: akhter a. J Immunol. 2012 Apr 1;188(7):3469-77. doi: 10.4049/jimmunol.1102272. Epub 2012 Feb 24. J Immunol. 2012. PMID: 22368275 Free PMC article.
Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery.
Abdulrahman BA, Khweek AA, Akhter A, Caution K, Tazi M, Hassan H, Zhang Y, Rowland PD, Malhotra S, Aeffner F, Davis IC, Valvano MA, Amer AO. Abdulrahman BA, et al. Among authors: akhter a. J Biol Chem. 2013 Jan 18;288(3):2049-58. doi: 10.1074/jbc.M112.411728. Epub 2012 Nov 12. J Biol Chem. 2013. PMID: 23148214 Free PMC article.
169 results