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TGF-beta signaling in tumor suppression and cancer progression.
Derynck R, Akhurst RJ, Balmain A. Derynck R, et al. Among authors: akhurst rj. Nat Genet. 2001 Oct;29(2):117-29. doi: 10.1038/ng1001-117. Nat Genet. 2001. PMID: 11586292 Review.
The role of TGF-beta s in mammalian development and neoplasia.
Akhurst RJ, Fitzpatrick DR, Fowlis DJ, Gatherer D, Millan FA, Slager H. Akhurst RJ, et al. Mol Reprod Dev. 1992 Jun;32(2):127-35. doi: 10.1002/mrd.1080320208. Mol Reprod Dev. 1992. PMID: 1637551 Review.
Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo.
Millan FA, Denhez F, Kondaiah P, Akhurst RJ. Millan FA, et al. Among authors: akhurst rj. Development. 1991 Jan;111(1):131-43. Development. 1991. PMID: 1707784
Loss of growth control by TGF-beta occurs at a late stage of mouse skin carcinogenesis and is independent of ras gene activation.
Haddow S, Fowlis DJ, Parkinson K, Akhurst RJ, Balmain A. Haddow S, et al. Among authors: akhurst rj. Oncogene. 1991 Aug;6(8):1465-70. Oncogene. 1991. PMID: 1886717
Expression of TGF-beta isoforms during first trimester human embryogenesis.
Gatherer D, Ten Dijke P, Baird DT, Akhurst RJ. Gatherer D, et al. Among authors: akhurst rj. Development. 1990 Oct;110(2):445-60. Development. 1990. PMID: 2133548
Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis.
Akhurst RJ, Fee F, Balmain A. Akhurst RJ, et al. Nature. 1988 Jan 28;331(6154):363-5. doi: 10.1038/331363a0. Nature. 1988. PMID: 3422343
Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice.
Cui W, Fowlis DJ, Cousins FM, Duffie E, Bryson S, Balmain A, Akhurst RJ. Cui W, et al. Among authors: akhurst rj. Genes Dev. 1995 Apr 15;9(8):945-55. doi: 10.1101/gad.9.8.945. Genes Dev. 1995. PMID: 7774812
Rapid induction and clearance of TGF beta 1 is an early response to wounding in the mouse embryo.
Martin P, Dickson MC, Millan FA, Akhurst RJ. Martin P, et al. Among authors: akhurst rj. Dev Genet. 1993;14(3):225-38. doi: 10.1002/dvg.1020140309. Dev Genet. 1993. PMID: 8358867
Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice.
Bonyadi M, Rusholme SA, Cousins FM, Su HC, Biron CA, Farrall M, Akhurst RJ. Bonyadi M, et al. Among authors: akhurst rj. Nat Genet. 1997 Feb;15(2):207-11. doi: 10.1038/ng0297-207. Nat Genet. 1997. PMID: 9020852
Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.
Portella G, Cumming SA, Liddell J, Cui W, Ireland H, Akhurst RJ, Balmain A. Portella G, et al. Among authors: akhurst rj. Cell Growth Differ. 1998 May;9(5):393-404. Cell Growth Differ. 1998. PMID: 9607560
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