Akhurst RJ - Search Results

1

Targeting the TGFβ signalling pathway in disease.

Akhurst RJ, Hata A. Akhurst RJ, et al. Nat Rev Drug Discov. 2012 Oct;11(10):790-811. doi: 10.1038/nrd3810. Epub 2012 Sep 24. Nat Rev Drug Discov. 2012. PMID: 23000686 Free PMC article. Review.

2

TGF-beta signaling in tumor suppression and cancer progression.

Derynck R, Akhurst RJ, Balmain A. Derynck R, et al. Among authors: akhurst rj. Nat Genet. 2001 Oct;29(2):117-29. doi: 10.1038/ng1001-117. Nat Genet. 2001. PMID: 11586292 Review.

3

TGF-beta signaling in cancer--a double-edged sword.

Akhurst RJ, Derynck R. Akhurst RJ, et al. Trends Cell Biol. 2001 Nov;11(11):S44-51. doi: 10.1016/s0962-8924(01)02130-4. Trends Cell Biol. 2001. PMID: 11684442 Review.

4

TGF-beta antagonists: why suppress a tumor suppressor?

Akhurst RJ. Akhurst RJ. J Clin Invest. 2002 Jun;109(12):1533-6. doi: 10.1172/JCI15970. J Clin Invest. 2002. PMID: 12070299 Free PMC article. Review. No abstract available.

5

Large- and small-molecule inhibitors of transforming growth factor-beta signaling.

Akhurst RJ. Akhurst RJ. Curr Opin Investig Drugs. 2006 Jun;7(6):513-21. Curr Opin Investig Drugs. 2006. PMID: 16784021 Review.

6

Mutations of TGFbeta signaling molecules in human disease.

Harradine KA, Akhurst RJ. Harradine KA, et al. Among authors: akhurst rj. Ann Med. 2006;38(6):403-14. doi: 10.1080/07853890600919911. Ann Med. 2006. PMID: 17008304 Review.

7

TGF beta inhibition for cancer therapy.

Saunier EF, Akhurst RJ. Saunier EF, et al. Among authors: akhurst rj. Curr Cancer Drug Targets. 2006 Nov;6(7):565-78. doi: 10.2174/156800906778742460. Curr Cancer Drug Targets. 2006. PMID: 17100564 Review.

8

Differentiation plasticity regulated by TGF-beta family proteins in development and disease.

Derynck R, Akhurst RJ. Derynck R, et al. Among authors: akhurst rj. Nat Cell Biol. 2007 Sep;9(9):1000-4. doi: 10.1038/ncb434. Nat Cell Biol. 2007. PMID: 17762890

9

The type I TGF-beta receptor is covalently modified and regulated by sumoylation.

Kang JS, Saunier EF, Akhurst RJ, Derynck R. Kang JS, et al. Among authors: akhurst rj. Nat Cell Biol. 2008 Jun;10(6):654-64. doi: 10.1038/ncb1728. Epub 2008 May 11. Nat Cell Biol. 2008. PMID: 18469808 Free PMC article.

10

Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients.

Harradine KA, Ridd K, Saunier EF, Clermont FF, Perez-Losada J, Moore DH, Epstein EH Jr, Bastian BC, Akhurst RJ. Harradine KA, et al. Among authors: akhurst rj. Clin Cancer Res. 2009 Aug 15;15(16):5101-7. doi: 10.1158/1078-0432.CCR-08-3286. Epub 2009 Aug 11. Clin Cancer Res. 2009. PMID: 19671862 Free PMC article.

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