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Toll-like receptors as adjuvant receptors.
Kaisho T, Akira S. Kaisho T, et al. Biochim Biophys Acta. 2002 Feb 13;1589(1):1-13. doi: 10.1016/s0167-4889(01)00182-3. Biochim Biophys Acta. 2002. PMID: 11909637 Review.
Toll-Like Receptor 9 Deficiency Breaks Tolerance to RNA-Associated Antigens and Up-Regulates Toll-Like Receptor 7 Protein in Sle1 Mice.
Celhar T, Yasuga H, Lee HY, Zharkova O, Tripathi S, Thornhill SI, Lu HK, Au B, Lim LHK, Thamboo TP, Akira S, Wakeland EK, Connolly JE, Fairhurst AM. Celhar T, et al. Arthritis Rheumatol. 2018 Oct;70(10):1597-1609. doi: 10.1002/art.40535. Arthritis Rheumatol. 2018. PMID: 29687651 Free PMC article.
Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice.
Kaiko GE, Loh Z, Spann K, Lynch JP, Lalwani A, Zheng Z, Davidson S, Uematsu S, Akira S, Hayball J, Diener KR, Baines KJ, Simpson JL, Foster PS, Phipps S. Kaiko GE, et al. J Allergy Clin Immunol. 2013 May;131(5):1331-9.e10. doi: 10.1016/j.jaci.2013.02.041. Epub 2013 Apr 2. J Allergy Clin Immunol. 2013. PMID: 23561801
Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling.
Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, Al-Quran S, Bovio I, Akira S, Kumagai Y, Moldawer LL. Scumpia PO, et al. J Immunol. 2010 Mar 1;184(5):2247-51. doi: 10.4049/jimmunol.0903652. Epub 2010 Feb 3. J Immunol. 2010. PMID: 20130216 Free PMC article.
S. aureus-induced HSPC expansion in MyD88(-/-)TRIF(-/-) mice is also normal, but is associated with BM remodeling as granulocyte stores are released peripherally. ...
S. aureus-induced HSPC expansion in MyD88(-/-)TRIF(-/-) mice is also normal, but is associated with BM remodeling as granulocyte stor
Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway.
Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, Foo SY, Hansbro N, Uematsu S, Akira S, Matthaei KI, Rosenberg HF, Foster PS, Phipps S. Davidson S, et al. J Immunol. 2011 May 15;186(10):5938-48. doi: 10.4049/jimmunol.1002635. Epub 2011 Apr 11. J Immunol. 2011. PMID: 21482736 Free PMC article.
MDA5/RIG-I and virus recognition.
Takeuchi O, Akira S. Takeuchi O, et al. Curr Opin Immunol. 2008 Feb;20(1):17-22. doi: 10.1016/j.coi.2008.01.002. Epub 2008 Feb 12. Curr Opin Immunol. 2008. PMID: 18272355 Review.
Recognition of viruses by innate immunity.
Takeuchi O, Akira S. Takeuchi O, et al. Immunol Rev. 2007 Dec;220:214-24. doi: 10.1111/j.1600-065X.2007.00562.x. Immunol Rev. 2007. PMID: 17979849 Review.
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