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1,268 results
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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. Yoneyama M, et al. Among authors: akira s. Nat Immunol. 2004 Jul;5(7):730-7. doi: 10.1038/ni1087. Epub 2004 Jun 20. Nat Immunol. 2004. PMID: 15208624
Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling.
Yamazaki K, Gohda J, Kanayama A, Miyamoto Y, Sakurai H, Yamamoto M, Akira S, Hayashi H, Su B, Inoue J. Yamazaki K, et al. Among authors: akira s. Sci Signal. 2009 Oct 20;2(93):ra66. doi: 10.1126/scisignal.2000387. Sci Signal. 2009. PMID: 19843958
Gene-specific requirement of a nuclear protein, IkappaB-zeta, for promoter association of inflammatory transcription regulators.
Yamazaki S, Matsuo S, Muta T, Yamamoto M, Akira S, Takeshige K. Yamazaki S, et al. Among authors: akira s. J Biol Chem. 2008 Nov 21;283(47):32404-11. doi: 10.1074/jbc.M802148200. Epub 2008 Sep 29. J Biol Chem. 2008. PMID: 18824552
Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.
Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T. Kitai Y, et al. Among authors: akira s. J Biol Chem. 2015 Jan 9;290(2):1269-80. doi: 10.1074/jbc.M114.611053. Epub 2014 Dec 1. J Biol Chem. 2015. PMID: 25451939 Free PMC article.
Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1.
Iwai A, Shiozaki T, Kawai T, Akira S, Kawaoka Y, Takada A, Kida H, Miyazaki T. Iwai A, et al. Among authors: akira s. J Biol Chem. 2010 Oct 15;285(42):32064-74. doi: 10.1074/jbc.M110.112458. Epub 2010 Aug 10. J Biol Chem. 2010. PMID: 20699220 Free PMC article.
TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway.
Yoshida R, Takaesu G, Yoshida H, Okamoto F, Yoshioka T, Choi Y, Akira S, Kawai T, Yoshimura A, Kobayashi T. Yoshida R, et al. Among authors: akira s. J Biol Chem. 2008 Dec 26;283(52):36211-20. doi: 10.1074/jbc.M806576200. Epub 2008 Nov 4. J Biol Chem. 2008. PMID: 18984593 Free PMC article.
Viral infections activate types I and III interferon genes through a common mechanism.
Onoguchi K, Yoneyama M, Takemura A, Akira S, Taniguchi T, Namiki H, Fujita T. Onoguchi K, et al. Among authors: akira s. J Biol Chem. 2007 Mar 9;282(10):7576-81. doi: 10.1074/jbc.M608618200. Epub 2007 Jan 4. J Biol Chem. 2007. PMID: 17204473
TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.
Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J. Uemura N, et al. Among authors: akira s. J Biol Chem. 2006 Mar 24;281(12):7863-72. doi: 10.1074/jbc.M509834200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446357 Free PMC article.
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells.
Rasschaert J, Ladrière L, Urbain M, Dogusan Z, Katabua B, Sato S, Akira S, Gysemans C, Mathieu C, Eizirik DL. Rasschaert J, et al. Among authors: akira s. J Biol Chem. 2005 Oct 7;280(40):33984-91. doi: 10.1074/jbc.M502213200. Epub 2005 Jul 15. J Biol Chem. 2005. PMID: 16027122
Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity.
Kuniyoshi K, Takeuchi O, Pandey S, Satoh T, Iwasaki H, Akira S, Kawai T. Kuniyoshi K, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5646-51. doi: 10.1073/pnas.1401674111. Epub 2014 Mar 27. Proc Natl Acad Sci U S A. 2014. PMID: 24706898 Free PMC article.
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