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Recognition of viruses by innate immunity.
Takeuchi O, Akira S. Takeuchi O, et al. Immunol Rev. 2007 Dec;220:214-24. doi: 10.1111/j.1600-065X.2007.00562.x. Immunol Rev. 2007. PMID: 17979849 Review.
Toll-Like Receptor 9 Deficiency Breaks Tolerance to RNA-Associated Antigens and Up-Regulates Toll-Like Receptor 7 Protein in Sle1 Mice.
Celhar T, Yasuga H, Lee HY, Zharkova O, Tripathi S, Thornhill SI, Lu HK, Au B, Lim LHK, Thamboo TP, Akira S, Wakeland EK, Connolly JE, Fairhurst AM. Celhar T, et al. Arthritis Rheumatol. 2018 Oct;70(10):1597-1609. doi: 10.1002/art.40535. Arthritis Rheumatol. 2018. PMID: 29687651 Free PMC article.
Innate lymphoid cells regulate intestinal epithelial cell glycosylation.
Goto Y, Obata T, Kunisawa J, Sato S, Ivanov II, Lamichhane A, Takeyama N, Kamioka M, Sakamoto M, Matsuki T, Setoyama H, Imaoka A, Uematsu S, Akira S, Domino SE, Kulig P, Becher B, Renauld JC, Sasakawa C, Umesaki Y, Benno Y, Kiyono H. Goto Y, et al. Science. 2014 Sep 12;345(6202):1254009. doi: 10.1126/science.1254009. Epub 2014 Aug 21. Science. 2014. PMID: 25214634 Free PMC article.
Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling.
Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, Al-Quran S, Bovio I, Akira S, Kumagai Y, Moldawer LL. Scumpia PO, et al. J Immunol. 2010 Mar 1;184(5):2247-51. doi: 10.4049/jimmunol.0903652. Epub 2010 Feb 3. J Immunol. 2010. PMID: 20130216 Free PMC article.
S. aureus-induced HSPC expansion in MyD88(-/-)TRIF(-/-) mice is also normal, but is associated with BM remodeling as granulocyte stores are released peripherally. ...
S. aureus-induced HSPC expansion in MyD88(-/-)TRIF(-/-) mice is also normal, but is associated with BM remodeling as granulocyte stor
Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway.
Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, Foo SY, Hansbro N, Uematsu S, Akira S, Matthaei KI, Rosenberg HF, Foster PS, Phipps S. Davidson S, et al. J Immunol. 2011 May 15;186(10):5938-48. doi: 10.4049/jimmunol.1002635. Epub 2011 Apr 11. J Immunol. 2011. PMID: 21482736 Free PMC article.
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.
Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo YM, Gale M Jr, Akira S, Yonehara S, Kato A, Fujita T. Yoneyama M, et al. J Immunol. 2005 Sep 1;175(5):2851-8. doi: 10.4049/jimmunol.175.5.2851. J Immunol. 2005. PMID: 16116171
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J. Poeck H, et al. Nat Immunol. 2010 Jan;11(1):63-9. doi: 10.1038/ni.1824. Epub 2009 Nov 15. Nat Immunol. 2010. PMID: 19915568
TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.
Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J. Konno H, et al. PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674. PLoS One. 2009. PMID: 19479062 Free PMC article.
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