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1,267 results
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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors.
Kawai T, Akira S. Kawai T, et al. Among authors: akira s. Nat Immunol. 2010 May;11(5):373-84. doi: 10.1038/ni.1863. Epub 2010 Apr 20. Nat Immunol. 2010. PMID: 20404851 Review.
Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.
Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T. Kitai Y, et al. Among authors: akira s. J Biol Chem. 2015 Jan 9;290(2):1269-80. doi: 10.1074/jbc.M114.611053. Epub 2014 Dec 1. J Biol Chem. 2015. PMID: 25451939 Free PMC article.
TLR1- and TLR6-independent recognition of bacterial lipopeptides.
Buwitt-Beckmann U, Heine H, Wiesmüller KH, Jung G, Brock R, Akira S, Ulmer AJ. Buwitt-Beckmann U, et al. Among authors: akira s. J Biol Chem. 2006 Apr 7;281(14):9049-57. doi: 10.1074/jbc.M512525200. Epub 2006 Feb 2. J Biol Chem. 2006. PMID: 16455646
Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity.
Kuniyoshi K, Takeuchi O, Pandey S, Satoh T, Iwasaki H, Akira S, Kawai T. Kuniyoshi K, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5646-51. doi: 10.1073/pnas.1401674111. Epub 2014 Mar 27. Proc Natl Acad Sci U S A. 2014. PMID: 24706898 Free PMC article.
Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus.
Lee H, Komano J, Saitoh Y, Yamaoka S, Kozaki T, Misawa T, Takahama M, Satoh T, Takeuchi O, Yamamoto N, Matsuura Y, Saitoh T, Akira S. Lee H, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12379-84. doi: 10.1073/pnas.1310604110. Epub 2013 Jul 8. Proc Natl Acad Sci U S A. 2013. PMID: 23836649 Free PMC article.
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.
Kondo T, Kobayashi J, Saitoh T, Maruyama K, Ishii KJ, Barber GN, Komatsu K, Akira S, Kawai T. Kondo T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2969-74. doi: 10.1073/pnas.1222694110. Epub 2013 Feb 6. Proc Natl Acad Sci U S A. 2013. PMID: 23388631 Free PMC article.
IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18.
Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O. Miyake T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17680-5. doi: 10.1073/pnas.1012977107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876105 Free PMC article.
Induction of type I interferon by adenovirus-encoded small RNAs.
Yamaguchi T, Kawabata K, Kouyama E, Ishii KJ, Katayama K, Suzuki T, Kurachi S, Sakurai F, Akira S, Mizuguchi H. Yamaguchi T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17286-91. doi: 10.1073/pnas.1009823107. Epub 2010 Sep 20. Proc Natl Acad Sci U S A. 2010. PMID: 20855616 Free PMC article.
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.
Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O. Satoh T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8. Proc Natl Acad Sci U S A. 2010. PMID: 20080593 Free PMC article.
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.
Saitoh T, Fujita N, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T, Yamamoto N, Kawai T, Ishii K, Takeuchi O, Yoshimori T, Akira S. Saitoh T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20842-6. doi: 10.1073/pnas.0911267106. Epub 2009 Nov 19. Proc Natl Acad Sci U S A. 2009. PMID: 19926846 Free PMC article.
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