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2,189 results
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NF-kappaB activation in development and progression of cancer.
Inoue J, Gohda J, Akiyama T, Semba K. Inoue J, et al. Among authors: akiyama t. Cancer Sci. 2007 Mar;98(3):268-74. doi: 10.1111/j.1349-7006.2007.00389.x. Cancer Sci. 2007. PMID: 17270016 Review.
Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling.
Takatsuna H, Kato H, Gohda J, Akiyama T, Moriya A, Okamoto Y, Yamagata Y, Otsuka M, Umezawa K, Semba K, Inoue J. Takatsuna H, et al. Among authors: akiyama t. J Biol Chem. 2003 Apr 4;278(14):12144-50. doi: 10.1074/jbc.M300720200. Epub 2003 Feb 3. J Biol Chem. 2003. PMID: 12566447
TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain.
Matsumura T, Semba K, Azuma S, Ikawa S, Gohda J, Akiyama T, Inoue J. Matsumura T, et al. Among authors: akiyama t. Biochem Biophys Res Commun. 2004 Apr 23;317(1):230-4. doi: 10.1016/j.bbrc.2004.03.030. Biochem Biophys Res Commun. 2004. PMID: 15047173
Dependence of self-tolerance on TRAF6-directed development of thymic stroma.
Akiyama T, Maeda S, Yamane S, Ogino K, Kasai M, Kajiura F, Matsumoto M, Inoue J. Akiyama T, et al. Science. 2005 Apr 8;308(5719):248-51. doi: 10.1126/science.1105677. Epub 2005 Feb 10. Science. 2005. PMID: 15705807
IL-18 produced by thymic epithelial cells induces development of dendritic cells with CD11b in the fetal thymus.
Ito H, Esashi E, Akiyama T, Inoue J, Miyajima A. Ito H, et al. Among authors: akiyama t. Int Immunol. 2006 Aug;18(8):1253-63. doi: 10.1093/intimm/dxl058. Epub 2006 Jun 13. Int Immunol. 2006. PMID: 16772369
Characteristics and biological functions of TRAF6.
Inoue J, Gohda J, Akiyama T. Inoue J, et al. Among authors: akiyama t. Adv Exp Med Biol. 2007;597:72-9. doi: 10.1007/978-0-387-70630-6_6. Adv Exp Med Biol. 2007. PMID: 17633018 Review.
Developmental stage-dependent collaboration between the TNF receptor-associated factor 6 and lymphotoxin pathways for B cell follicle organization in secondary lymphoid organs.
Qin J, Konno H, Ohshima D, Yanai H, Motegi H, Shimo Y, Hirota F, Matsumoto M, Takaki S, Inoue J, Akiyama T. Qin J, et al. Among authors: akiyama t. J Immunol. 2007 Nov 15;179(10):6799-807. doi: 10.4049/jimmunol.179.10.6799. J Immunol. 2007. PMID: 17982070
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.
Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, Maruyama Y, Asaumi Y, Kitazawa J, Takayanagi H, Penninger JM, Matsumoto M, Nitta T, Takahama Y, Inoue J. Akiyama T, et al. Immunity. 2008 Sep 19;29(3):423-37. doi: 10.1016/j.immuni.2008.06.015. Immunity. 2008. PMID: 18799149
TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.
Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J. Konno H, et al. Among authors: akiyama t. PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674. PLoS One. 2009. PMID: 19479062 Free PMC article.
Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling.
Ando K, Hasegawa K, Shindo K, Furusawa T, Fujino T, Kikugawa K, Nakano H, Takeuchi O, Akira S, Akiyama T, Gohda J, Inoue J, Hayakawa M. Ando K, et al. Among authors: akiyama t. FEBS J. 2010 May;277(9):2051-66. doi: 10.1111/j.1742-4658.2010.07620.x. Epub 2010 Mar 19. FEBS J. 2010. PMID: 20345905
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