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Functional and metabolic adaptation in uraemic cardiomyopathy.
Smith K, Semple D, Aksentijevic D, Bhandari S, Seymour AM. Smith K, et al. Front Biosci (Elite Ed). 2010 Jun 1;2:1492-501. doi: 10.2741/e208. Front Biosci (Elite Ed). 2010. PMID: 20515820
Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart.
Faller KM, Medway DJ, Aksentijevic D, Sebag-Montefiore L, Schneider JE, Lygate CA, Neubauer S. Faller KM, et al. PLoS One. 2013 Jun 18;8(6):e66461. doi: 10.1371/journal.pone.0066461. Print 2013. PLoS One. 2013. PMID: 23823183 Free PMC article.
Multiple quantum filtered (23)Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na]i.
Eykyn TR, Aksentijević D, Aughton KL, Southworth R, Fuller W, Shattock MJ. Eykyn TR, et al. J Mol Cell Cardiol. 2015 Sep;86:95-101. doi: 10.1016/j.yjmcc.2015.07.009. Epub 2015 Jul 18. J Mol Cell Cardiol. 2015. PMID: 26196304 Free PMC article.
Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation.
Mansor LS, Mehta K, Aksentijevic D, Carr CA, Lund T, Cole MA, Le Page L, Sousa Fialho Mda L, Shattock MJ, Aasum E, Clarke K, Tyler DJ, Heather LC. Mansor LS, et al. J Physiol. 2016 Jan 15;594(2):307-20. doi: 10.1113/JP271242. Epub 2015 Dec 20. J Physiol. 2016. PMID: 26574233 Free PMC article.
On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.
Cole MA, Abd Jamil AH, Heather LC, Murray AJ, Sutton ER, Slingo M, Sebag-Montefiore L, Tan SC, Aksentijević D, Gildea OS, Stuckey DJ, Yeoh KK, Carr CA, Evans RD, Aasum E, Schofield CJ, Ratcliffe PJ, Neubauer S, Robbins PA, Clarke K. Cole MA, et al. Among authors: aksentijevic d. FASEB J. 2016 Aug;30(8):2684-97. doi: 10.1096/fj.201500094R. Epub 2016 Apr 21. FASEB J. 2016. PMID: 27103577 Free PMC article.
Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
Lygate CA, Bohl S, ten Hove M, Faller KM, Ostrowski PJ, Zervou S, Medway DJ, Aksentijevic D, Sebag-Montefiore L, Wallis J, Clarke K, Watkins H, Schneider JE, Neubauer S. Lygate CA, et al. Cardiovasc Res. 2012 Dec 1;96(3):466-75. doi: 10.1093/cvr/cvs272. Epub 2012 Aug 21. Cardiovasc Res. 2012. PMID: 22915766 Free PMC article.
Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age.
Lygate CA, Medway DJ, Ostrowski PJ, Aksentijevic D, Sebag-Montefiore L, Hunyor I, Zervou S, Schneider JE, Neubauer S. Lygate CA, et al. Basic Res Cardiol. 2012 Sep;107(5):276. doi: 10.1007/s00395-012-0276-2. Epub 2012 Jul 4. Basic Res Cardiol. 2012. PMID: 22760499 Free PMC article.
Is there a causal link between intracellular Na elevation and metabolic remodelling in cardiac hypertrophy?
Aksentijevic D, O'Brien BA, Eykyn TR, Shattock MJ. Aksentijevic D, et al. Biochem Soc Trans. 2018 Aug 20;46(4):817-827. doi: 10.1042/BST20170508. Epub 2018 Jul 3. Biochem Soc Trans. 2018. PMID: 29970448 Free PMC article. Review.
Is rate-pressure product of any use in the isolated rat heart? Assessing cardiac 'effort' and oxygen consumption in the Langendorff-perfused heart.
Aksentijević D, Lewis HR, Shattock MJ. Aksentijević D, et al. Exp Physiol. 2016 Feb;101(2):282-94. doi: 10.1113/EP085380. Epub 2015 Dec 16. Exp Physiol. 2016. PMID: 26585840 Free PMC article.
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