Al-Karmalawy AA - Search Results

1

Molecular docking, molecular dynamics, and in vitro studies reveal the potential of angiotensin II receptor blockers to inhibit the COVID-19 main protease.

Alnajjar R, Mostafa A, Kandeil A, Al-Karmalawy AA. Alnajjar R, et al. Heliyon. 2020 Dec;6(12):e05641. doi: 10.1016/j.heliyon.2020.e05641. Epub 2020 Dec 3. Heliyon. 2020. PMID: 33294721 Free PMC article.

2

4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments.

Ragab MA, Eldehna WM, Nocentini A, Bonardi A, Okda HE, Elgendy B, Ibrahim TS, Abd-Alhaseeb MM, Gratteri P, Supuran CT, Al-Karmalawy AA, Elagawany M. Ragab MA, et al. Eur J Med Chem. 2023 Mar 15;250:115180. doi: 10.1016/j.ejmech.2023.115180. Epub 2023 Feb 3. Eur J Med Chem. 2023. PMID: 36796297

3

Novel Hybrid Indole-Based Caffeic Acid Amide Derivatives as Potent Free Radical Scavenging Agents: Rational Design, Synthesis, Spectroscopic Characterization, In Silico and In Vitro Investigations.

Elkamhawy A, Oh NK, Gouda NA, Abdellattif MH, Alshammari SO, Abourehab MAS, Alshammari QA, Belal A, Kim M, Al-Karmalawy AA, Lee K. Elkamhawy A, et al. Metabolites. 2023 Jan 17;13(2):141. doi: 10.3390/metabo13020141. Metabolites. 2023. PMID: 36837759 Free PMC article.

4

Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies.

Zaki AA, Ashour A, Elhady SS, Darwish KM, Al-Karmalawy AA. Zaki AA, et al. J Tradit Complement Med. 2022 Jan;12(1):16-34. doi: 10.1016/j.jtcme.2021.05.001. Epub 2021 May 17. J Tradit Complement Med. 2022. PMID: 34026584 Free PMC article.

5

Strong Inhibitory Activity and Action Modes of Synthetic Maslinic Acid Derivative on Highly Pathogenic Coronaviruses: COVID-19 Drug Candidate.

Soltane R, Chrouda A, Mostafa A, Al-Karmalawy AA, Chouaïb K, Dhahri A, Pashameah RA, Alasiri A, Kutkat O, Shehata M, Jannet HB, Gharbi J, Ali MA. Soltane R, et al. Pathogens. 2021 May 19;10(5):623. doi: 10.3390/pathogens10050623. Pathogens. 2021. PMID: 34069460 Free PMC article.

6

Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2.

Kandeil A, Mostafa A, Kutkat O, Moatasim Y, Al-Karmalawy AA, Rashad AA, Kayed AE, Kayed AE, El-Shesheny R, Kayali G, Ali MA. Kandeil A, et al. Pathogens. 2021 Jun 15;10(6):758. doi: 10.3390/pathogens10060758. Pathogens. 2021. PMID: 34203977 Free PMC article.

7

Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies.

Mahmoud A, Mostafa A, Al-Karmalawy AA, Zidan A, Abulkhair HS, Mahmoud SH, Shehata M, Elhefnawi MM, Ali MA. Mahmoud A, et al. Heliyon. 2021 Sep;7(9):e07962. doi: 10.1016/j.heliyon.2021.e07962. Epub 2021 Sep 9. Heliyon. 2021. PMID: 34518806 Free PMC article.

8

Delineating a potent antiviral activity of Cuphea ignea extract loaded nano-formulation against SARS-CoV-2: In silico and in vitro studies.

Mahmoud DB, Ismail WM, Moatasim Y, Kutkat O, ElMeshad AN, Ezzat SM, El Deeb KS, El-Fishawy AM, Gomaa MR, Kandeil A, Al-Karmalawy AA, Ali MA, Mostafa A. Mahmoud DB, et al. J Drug Deliv Sci Technol. 2021 Dec;66:102845. doi: 10.1016/j.jddst.2021.102845. Epub 2021 Sep 15. J Drug Deliv Sci Technol. 2021. PMID: 34539819 Free PMC article.

9

Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo Studies.

El Gizawy HA, Boshra SA, Mostafa A, Mahmoud SH, Ismail MI, Alsfouk AA, Taher AT, Al-Karmalawy AA. El Gizawy HA, et al. Molecules. 2021 Sep 27;26(19):5844. doi: 10.3390/molecules26195844. Molecules. 2021. PMID: 34641388 Free PMC article.

10

In Silico and In Vivo Evaluation of SARS-CoV-2 Predicted Epitopes-Based Candidate Vaccine.

Shehata MM, Mahmoud SH, Tarek M, Al-Karmalawy AA, Mahmoud A, Mostafa A, M Elhefnawi M, Ali MA. Shehata MM, et al. Molecules. 2021 Oct 13;26(20):6182. doi: 10.3390/molecules26206182. Molecules. 2021. PMID: 34684763 Free PMC article.

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