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Exploring S1 plasticity and probing S1' subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors.
Bioorg Med Chem. 2015 Jul 1;23(13):3192-207. doi: 10.1016/j.bmc.2015.04.066. Epub 2015 May 1.
Bioorg Med Chem. 2015.
PMID: 25982416
Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13.
Albrecht S, Al-Lakkis-Wehbe M, Orsini A, Defoin A, Pale P, Salomon E, Tarnus C, Weibel JM.
Albrecht S, et al. Among authors: al lakkis wehbe m.
Bioorg Med Chem. 2011 Feb 15;19(4):1434-49. doi: 10.1016/j.bmc.2011.01.008. Epub 2011 Jan 11.
Bioorg Med Chem. 2011.
PMID: 21292493
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Synthesis of amino-hydroxy-benzocycloheptenones as potent, selective, non-peptidic dinuclear zinc metalloaminopeptidase inhibitors.
Al-Lakkis-Wehbe M, Chaillou B, Defoin A, Albrecht S, Tarnus C.
Al-Lakkis-Wehbe M, et al.
Bioorg Med Chem. 2013 Nov 1;21(21):6447-55. doi: 10.1016/j.bmc.2013.08.044. Epub 2013 Sep 4.
Bioorg Med Chem. 2013.
PMID: 24055078
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