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Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS.
Bajaj NP, al-Sarraj ST, Leigh PN, Anderson V, Miller CC. Bajaj NP, et al. Prog Neuropsychopharmacol Biol Psychiatry. 1999 Jul;23(5):833-50. doi: 10.1016/s0278-5846(99)00044-5. Prog Neuropsychopharmacol Biol Psychiatry. 1999. PMID: 10509378
235 results