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Year Number of Results
2002 1
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2005 3
2006 1
2007 3
2008 8
2009 4
2010 3
2011 5
2012 7
2013 9
2014 8
2015 7
2016 12
2017 9
2018 5
2019 13
2020 15
2021 14
2022 6
2023 10
2024 3
2025 1

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136 results

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Page 1
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Demaria M, Ohtani N, Youssef SA, Rodier F, Toussaint W, Mitchell JR, Laberge RM, Vijg J, Van Steeg H, Dollé ME, Hoeijmakers JH, de Bruin A, Hara E, Campisi J. Demaria M, et al. Among authors: de bruin a. Dev Cell. 2014 Dec 22;31(6):722-33. doi: 10.1016/j.devcel.2014.11.012. Epub 2014 Dec 11. Dev Cell. 2014. PMID: 25499914 Free PMC article.
Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.
Demaria M, O'Leary MN, Chang J, Shao L, Liu S, Alimirah F, Koenig K, Le C, Mitin N, Deal AM, Alston S, Academia EC, Kilmarx S, Valdovinos A, Wang B, de Bruin A, Kennedy BK, Melov S, Zhou D, Sharpless NE, Muss H, Campisi J. Demaria M, et al. Among authors: de bruin a. Cancer Discov. 2017 Feb;7(2):165-176. doi: 10.1158/2159-8290.CD-16-0241. Epub 2016 Dec 15. Cancer Discov. 2017. PMID: 27979832 Free PMC article.
T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice.
Bazioti V, La Rose AM, Maassen S, Bianchi F, de Boer R, Halmos B, Dabral D, Guilbaud E, Flohr-Svendsen A, Groenen AG, Marmolejo-Garza A, Koster MH, Kloosterhuis NJ, Havinga R, Pranger AT, Langelaar-Makkinje M, de Bruin A, van de Sluis B, Kohan AB, Yvan-Charvet L, van den Bogaart G, Westerterp M. Bazioti V, et al. Among authors: de bruin a. Nat Commun. 2022 Jul 1;13(1):3799. doi: 10.1038/s41467-022-31135-4. Nat Commun. 2022. PMID: 35778407 Free PMC article.
Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition.
Ling C, Versloot CJ, Arvidsson Kvissberg ME, Hu G, Swain N, Horcas-Nieto JM, Miraglia E, Thind MK, Farooqui A, Gerding A, van Eunen K, Koster MH, Kloosterhuis NJ, Chi L, ChenMi Y, Langelaar-Makkinje M, Bourdon C, Swann J, Smit M, de Bruin A, Youssef SA, Feenstra M, van Dijk TH, Thedieck K, Jonker JW, Kim PK, Bakker BM, Bandsma RHJ. Ling C, et al. Among authors: de bruin a. EBioMedicine. 2023 Oct;96:104809. doi: 10.1016/j.ebiom.2023.104809. Epub 2023 Sep 20. EBioMedicine. 2023. PMID: 37738832 Free PMC article.
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
van Zwol W, Rimbert A, Wolters JC, Smit M, Bloks VW, Kloosterhuis NJ, Huijkman NCA, Koster MH, Tharehalli U, de Neck SM, Bournez C, Fuh MM, Kuipers J, Rajan S, de Bruin A, Ginsberg HN, van Westen GJP, Hussain MM, Scheja L, Heeren J, Zimmerman P, van de Sluis B, Kuivenhoven JA. van Zwol W, et al. Among authors: de bruin a. Hepatology. 2023 Nov 1;78(5):1418-1432. doi: 10.1002/hep.32709. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36053190 Free PMC article.
Cellular polyploidy in organ homeostasis and regeneration.
Fang J, de Bruin A, Villunger A, Schiffelers R, Lei Z, Sluijter JPG. Fang J, et al. Among authors: de bruin a. Protein Cell. 2023 Aug 1;14(8):560-578. doi: 10.1093/procel/pwac064. Protein Cell. 2023. PMID: 37526344 Free PMC article.
Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis.
Schultz DF, Davies BA, Payne JA, Martin CP, Minard AY, Childs BG, Zhang C, Jeganathan KB, Sturmlechner I, White TA, de Bruin A, Harkema L, Chen H, Davies MA, Jachim S, LeBrasseur NK, Piper RC, Li H, Baker DJ, van Deursen J, Billadeau DD, Katzmann DJ. Schultz DF, et al. Among authors: de bruin a. J Cell Sci. 2024 Sep 15;137(18):jcs262032. doi: 10.1242/jcs.262032. Epub 2024 Sep 27. J Cell Sci. 2024. PMID: 39155850
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
Sladky VC, Knapp K, Szabo TG, Braun VZ, Bongiovanni L, van den Bos H, Spierings DC, Westendorp B, Curinha A, Stojakovic T, Scharnagl H, Timelthaler G, Tsuchia K, Pinter M, Semmler G, Foijer F, de Bruin A, Reiberger T, Rohr-Udilova N, Villunger A. Sladky VC, et al. Among authors: de bruin a. EMBO Rep. 2020 Dec 3;21(12):e50893. doi: 10.15252/embr.202050893. Epub 2020 Nov 23. EMBO Rep. 2020. PMID: 33225610 Free PMC article.
136 results