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Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination.
Alani E, Padmore R, Kleckner N. Alani E, et al. Cell. 1990 May 4;61(3):419-36. doi: 10.1016/0092-8674(90)90524-i. Cell. 1990. PMID: 2185891
Furthermore, all rad50 mutants block formation of tripartite SC structure but permit other aspects of SC development, i.e., formation of axial cores. ...
Furthermore, all rad50 mutants block formation of tripartite SC structure but permit other aspects of SC development, i.e., formation …
Baker's Yeast Clinical Isolates Provide a Model for How Pathogenic Yeasts Adapt to Stress.
Raghavan V, Aquadro CF, Alani E. Raghavan V, et al. Among authors: alani e. Trends Genet. 2019 Nov;35(11):804-817. doi: 10.1016/j.tig.2019.08.002. Epub 2019 Sep 13. Trends Genet. 2019. PMID: 31526615 Review.
Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein.
Alani E, Thresher R, Griffith JD, Kolodner RD. Alani E, et al. J Mol Biol. 1992 Sep 5;227(1):54-71. doi: 10.1016/0022-2836(92)90681-9. J Mol Biol. 1992. PMID: 1522601
In an assay that measures the pairing of circular ssDNA with homologous linear duplex DNA, y-RPA stimulated the strand-exchange activity of Sepl approximately threefold and the activity of RecA protein to the same extent as did E. coli SSB. ...These results demonstrate tha …
In an assay that measures the pairing of circular ssDNA with homologous linear duplex DNA, y-RPA stimulated the strand-exchange activity of …
A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae.
Cao L, Alani E, Kleckner N. Cao L, et al. Among authors: alani e. Cell. 1990 Jun 15;61(6):1089-101. doi: 10.1016/0092-8674(90)90072-m. Cell. 1990. PMID: 2190690
The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions.
Alani E, Subbiah S, Kleckner N. Alani E, et al. Genetics. 1989 May;122(1):47-57. Genetics. 1989. PMID: 2659437 Free PMC article.
A new type of fusion analysis applicable to many organisms: protein fusions to the URA3 gene of yeast.
Alani E, Kleckner N. Alani E, et al. Genetics. 1987 Sep;117(1):5-12. Genetics. 1987. PMID: 3311876 Free PMC article.
We have made constructs that join the promoter sequences and a portion of the coding region of the Saccharomyces cerevisiae HIS4 and GAL1 genes and the E. coli lacZ gene to the sixth codon of the S. cerevisiae URA3 gene (encodes orotidine-5'-phosphate (OMP) decarboxylase) …
We have made constructs that join the promoter sequences and a portion of the coding region of the Saccharomyces cerevisiae HIS4 and GAL1 ge …
Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae.
Guarente L, Lalonde B, Gifford P, Alani E. Guarente L, et al. Among authors: alani e. Cell. 1984 Feb;36(2):503-11. doi: 10.1016/0092-8674(84)90243-5. Cell. 1984. PMID: 6319028
The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions.
Alani E, Chi NW, Kolodner R. Alani E, et al. Genes Dev. 1995 Jan 15;9(2):234-47. doi: 10.1101/gad.9.2.234. Genes Dev. 1995. PMID: 7851796
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae.
Alani E, Reenan RA, Kolodner RD. Alani E, et al. Genetics. 1994 May;137(1):19-39. Genetics. 1994. PMID: 8056309 Free PMC article.
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast.
Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. Prolla TA, et al. Among authors: alani e. Science. 1994 Aug 19;265(5175):1091-3. doi: 10.1126/science.8066446. Science. 1994. PMID: 8066446
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