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T lymphocyte receptor deficiencies.
Kappes DJ, Alarcón B, Regueiro JR. Kappes DJ, et al. Among authors: alarcon b. Curr Opin Immunol. 1995 Aug;7(4):441-7. doi: 10.1016/0952-7915(95)80086-7. Curr Opin Immunol. 1995. PMID: 7495506 Review.
The extracellular part of zeta is buried in the T cell antigen receptor complex.
Minguet S, Swamy M, Dopfer EP, Dengler E, Alarcón B, Schamel WW. Minguet S, et al. Among authors: alarcon b. Immunol Lett. 2008 Mar 15;116(2):203-10. doi: 10.1016/j.imlet.2007.11.024. Epub 2007 Dec 31. Immunol Lett. 2008. PMID: 18215426
A conformation- and avidity-based proofreading mechanism for the TCR-CD3 complex.
Schamel WW, Risueño RM, Minguet S, Ortíz AR, Alarcón B. Schamel WW, et al. Among authors: alarcon b. Trends Immunol. 2006 Apr;27(4):176-82. doi: 10.1016/j.it.2006.02.005. Epub 2006 Mar 9. Trends Immunol. 2006. PMID: 16527543
T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity.
Alarcón B, Swamy M, van Santen HM, Schamel WW. Alarcón B, et al. EMBO Rep. 2006 May;7(5):490-5. doi: 10.1038/sj.embor.7400682. EMBO Rep. 2006. PMID: 16670682 Free PMC article. Review.
Human TCR that incorporate CD3zeta induce highly preferred pairing between TCRalpha and beta chains following gene transfer.
Sebestyén Z, Schooten E, Sals T, Zaldivar I, San José E, Alarcón B, Bobisse S, Rosato A, Szöllosi J, Gratama JW, Willemsen RA, Debets R. Sebestyén Z, et al. Among authors: alarcon b. J Immunol. 2008 Jun 1;180(11):7736-46. doi: 10.4049/jimmunol.180.11.7736. J Immunol. 2008. PMID: 18490778
Full activation of the T cell receptor requires both clustering and conformational changes at CD3.
Minguet S, Swamy M, Alarcón B, Luescher IF, Schamel WW. Minguet S, et al. Among authors: alarcon b. Immunity. 2007 Jan;26(1):43-54. doi: 10.1016/j.immuni.2006.10.019. Epub 2006 Dec 21. Immunity. 2007. PMID: 17188005
Aurora A drives early signalling and vesicle dynamics during T-cell activation.
Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces NB, Sánchez-Madrid F. Blas-Rus N, et al. Among authors: alarcon b. Nat Commun. 2016 Apr 19;7:11389. doi: 10.1038/ncomms11389. Nat Commun. 2016. PMID: 27091106 Free PMC article.
The immunological synapse: a cause or consequence of T-cell receptor triggering?
Alarcón B, Mestre D, Martínez-Martín N. Alarcón B, et al. Immunology. 2011 Aug;133(4):420-5. doi: 10.1111/j.1365-2567.2011.03458.x. Epub 2011 Jun 2. Immunology. 2011. PMID: 21631496 Free PMC article. Review.
Differential cytosolic tail dependence and intracellular fate of T-cell receptors internalized upon activation with superantigen or phorbol ester.
Niedergang F, San José E, Rubin B, Alarcón B, Dautry-Varsat A, Alcover A. Niedergang F, et al. Among authors: alarcon b. Res Immunol. 1997 May;148(4):231-45. doi: 10.1016/s0923-2494(97)80865-6. Res Immunol. 1997. PMID: 9300530
Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model.
San José E, Sahuquillo AG, Bragado R, Alarcón B. San José E, et al. Among authors: alarcon b. Eur J Immunol. 1998 Jan;28(1):12-21. doi: 10.1002/(SICI)1521-4141(199801)28:01<12::AID-IMMU12>3.0.CO;2-9. Eur J Immunol. 1998. PMID: 9485181
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