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Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
Chandrasekaran A, Dittlau KS, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TT, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D, Gorodkin J, Muddashetty RS, Meyer M, Aldana BI, Freude KK. Chandrasekaran A, et al. Among authors: aldana bi. Stem Cell Reports. 2021 Nov 9;16(11):2736-2751. doi: 10.1016/j.stemcr.2021.09.013. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678206 Free PMC article.
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.
Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, Aldana BI, Freude K. Haukedal H, et al. Among authors: aldana bi. Brain Behav Immun. 2023 Oct;113:353-373. doi: 10.1016/j.bbi.2023.07.024. Epub 2023 Aug 3. Brain Behav Immun. 2023. PMID: 37543250 Free article.
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells.
Møller SH, Mellergaard M, Madsen M, Bermejo AV, Jepsen SD, Hansen MH, Høgh RI, Aldana BI, Desler C, Rasmussen LJ, Sustarsic EG, Gerhart-Hines Z, Daskalaki E, Wheelock CE, Hiron TK, Lin D, O'Callaghan CA, Wandall HH, Andresen L, Skov S. Møller SH, et al. Among authors: aldana bi. Front Immunol. 2020 Aug 11;11:1968. doi: 10.3389/fimmu.2020.01968. eCollection 2020. Front Immunol. 2020. PMID: 32849657 Free PMC article.
Essential Roles of Lactate in Müller Cell Survival and Function.
Vohra R, Aldana BI, Skytt DM, Freude K, Waagepetersen H, Bergersen LH, Kolko M. Vohra R, et al. Among authors: aldana bi. Mol Neurobiol. 2018 Dec;55(12):9108-9121. doi: 10.1007/s12035-018-1056-2. Epub 2018 Apr 11. Mol Neurobiol. 2018. PMID: 29644598
Lactate-Mediated Protection of Retinal Ganglion Cells.
Vohra R, Aldana BI, Bulli G, Skytt DM, Waagepetersen H, Bergersen LH, Kolko M. Vohra R, et al. Among authors: aldana bi. J Mol Biol. 2019 Apr 19;431(9):1878-1888. doi: 10.1016/j.jmb.2019.03.005. Epub 2019 Mar 13. J Mol Biol. 2019. PMID: 30878479
57 results