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Replicative adenoviruses for cancer therapy.
Alemany R, Balagué C, Curiel DT. Alemany R, et al. Nat Biotechnol. 2000 Jul;18(7):723-7. doi: 10.1038/77283. Nat Biotechnol. 2000. PMID: 10888838 Review.
Gene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses.
Alemany R, Gomez-Manzano C, Balagué C, Yung WK, Curiel DT, Kyritsis AP, Fueyo J. Alemany R, et al. Exp Cell Res. 1999 Oct 10;252(1):1-12. doi: 10.1006/excr.1999.4623. Exp Cell Res. 1999. PMID: 10502394 Review.
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo.
Fueyo J, Gomez-Manzano C, Yung WK, Liu TJ, Alemany R, McDonnell TJ, Shi X, Rao JS, Levin VA, Kyritsis AP. Fueyo J, et al. Among authors: alemany r. Nat Med. 1998 Jun;4(6):685-90. doi: 10.1038/nm0698-685. Nat Med. 1998. PMID: 9623977
Complementary adenoviral vectors for oncolysis.
Alemany R, Lai S, Lou YC, Jan HY, Fang X, Zhang WW. Alemany R, et al. Cancer Gene Ther. 1999 Jan-Feb;6(1):21-5. doi: 10.1038/sj.cgt.7700001. Cancer Gene Ther. 1999. PMID: 10078960
CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors.
Alemany R, Curiel DT. Alemany R, et al. Gene Ther. 2001 Sep;8(17):1347-53. doi: 10.1038/sj.gt.3301515. Gene Ther. 2001. PMID: 11571572
Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule.
Hemminki A, Dmitriev I, Liu B, Desmond RA, Alemany R, Curiel DT. Hemminki A, et al. Among authors: alemany r. Cancer Res. 2001 Sep 1;61(17):6377-81. Cancer Res. 2001. PMID: 11522629
Human papillomavirus E6E7-mediated adenovirus cell killing: selectivity of mutant adenovirus replication in organotypic cultures of human keratinocytes.
Balagué C, Noya F, Alemany R, Chow LT, Curiel DT. Balagué C, et al. Among authors: alemany r. J Virol. 2001 Aug;75(16):7602-11. doi: 10.1128/JVI.75.16.7602-7611.2001. J Virol. 2001. PMID: 11462032 Free PMC article.
[Oncolytic adenovirus for the treatment of cerebral tumors: past, present and future].
Alemany R, Gómez-Manzano C, Fueyo J. Alemany R, et al. Neurologia. 2001 Mar;16(3):122-7. Neurologia. 2001. PMID: 11333782 Review. Spanish.
Characterization of the cyclooxygenase-2 promoter in an adenoviral vector and its application for the mitigation of toxicity in suicide gene therapy of gastrointestinal cancers.
Yamamoto M, Alemany R, Adachi Y, Grizzle WE, Curiel DT. Yamamoto M, et al. Among authors: alemany r. Mol Ther. 2001 Mar;3(3):385-94. doi: 10.1006/mthe.2001.0275. Mol Ther. 2001. PMID: 11273781
A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.
Suzuki K, Fueyo J, Krasnykh V, Reynolds PN, Curiel DT, Alemany R. Suzuki K, et al. Among authors: alemany r. Clin Cancer Res. 2001 Jan;7(1):120-6. Clin Cancer Res. 2001. PMID: 11205899
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