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Page 1
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation.
Guillén-Boixet J, Kopach A, Holehouse AS, Wittmann S, Jahnel M, Schlüßler R, Kim K, Trussina IREA, Wang J, Mateju D, Poser I, Maharana S, Ruer-Gruß M, Richter D, Zhang X, Chang YT, Guck J, Honigmann A, Mahamid J, Hyman AA, Pappu RV, Alberti S, Franzmann TM. Guillén-Boixet J, et al. Among authors: holehouse as. Cell. 2020 Apr 16;181(2):346-361.e17. doi: 10.1016/j.cell.2020.03.049. Cell. 2020. PMID: 32302572 Free PMC article.
Identification of plant transcriptional activation domains.
Morffy N, Van den Broeck L, Miller C, Emenecker RJ, Bryant JA Jr, Lee TM, Sageman-Furnas K, Wilkinson EG, Pathak S, Kotha SR, Lam A, Mahatma S, Pande V, Waoo A, Wright RC, Holehouse AS, Staller MV, Sozzani R, Strader LC. Morffy N, et al. Among authors: holehouse as. Nature. 2024 Aug;632(8023):166-173. doi: 10.1038/s41586-024-07707-3. Epub 2024 Jul 17. Nature. 2024. PMID: 39020176 Free PMC article.
A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation.
Dorone Y, Boeynaems S, Flores E, Jin B, Hateley S, Bossi F, Lazarus E, Pennington JG, Michiels E, De Decker M, Vints K, Baatsen P, Bassel GW, Otegui MS, Holehouse AS, Exposito-Alonso M, Sukenik S, Gitler AD, Rhee SY. Dorone Y, et al. Among authors: holehouse as. Cell. 2021 Aug 5;184(16):4284-4298.e27. doi: 10.1016/j.cell.2021.06.009. Epub 2021 Jul 6. Cell. 2021. PMID: 34233164 Free PMC article.
Molecular determinants of condensate composition.
Holehouse AS, Alberti S. Holehouse AS, et al. Mol Cell. 2025 Jan 16;85(2):290-308. doi: 10.1016/j.molcel.2024.12.021. Epub 2025 Jan 16. Mol Cell. 2025. PMID: 39824169 Free PMC article. Review.
Transcription factor dimerization activates the p300 acetyltransferase.
Ortega E, Rengachari S, Ibrahim Z, Hoghoughi N, Gaucher J, Holehouse AS, Khochbin S, Panne D. Ortega E, et al. Among authors: holehouse as. Nature. 2018 Oct;562(7728):538-544. doi: 10.1038/s41586-018-0621-1. Epub 2018 Oct 15. Nature. 2018. PMID: 30323286 Free PMC article.
120 results