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2015 1
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Page 1
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy.
Xu A, Weissman D, Ermer KJ, Bertero E, Federspiel JM, Stadler F, Grünler E, Tangos M, Zervou S, Waddingham MT, Pearson JT, Reil JC, Scholtz S, Dudek J, Kohlhaas M, Nickel AG, Carrier L, Eschenhagen T, Michels M, Dos Remedios C, Lal S, Prates Roma L, Hamdani N, Kuster DWD, Falcão-Pires I, Johnson CN, Lygate CA, van der Velden J, Maack C, Sequeira V. Xu A, et al. Among authors: nickel ag. Circulation. 2025 Dec 16;152(24):1705-1727. doi: 10.1161/CIRCULATIONAHA.125.074120. Epub 2025 Oct 20. Circulation. 2025. PMID: 41111389
Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner.
ElBeck Z, Hossain MB, Siga H, Oskolkov N, Karlsson F, Lindgren J, Walentinsson A, Koppenhöfer D, Jarvis R, Bürli R, Jamier T, Franssen E, Firth M, Degasperi A, Bendtsen C, Menzies RI, Streckfuss-Bömeke K, Kohlhaas M, Nickel AG, Lund LH, Maack C, Végvári Á, Betsholtz C. ElBeck Z, et al. Among authors: nickel ag. Nat Commun. 2024 Mar 20;15(1):2358. doi: 10.1038/s41467-024-46384-8. Nat Commun. 2024. PMID: 38509128 Free PMC article.
Mitochondrial energetics and calcium coupling in the heart.
Kohlhaas M, Nickel AG, Maack C. Kohlhaas M, et al. Among authors: nickel ag. J Physiol. 2017 Jun 15;595(12):3753-3763. doi: 10.1113/JP273609. Epub 2017 Mar 10. J Physiol. 2017. PMID: 28105746 Free PMC article. Review.
From kidney injury to cardiac dysfunction: the central role of oxidative stress in diabetes and CKD.
Sen P, Sittig T, Hamers J, d'Ambrosio L, Ornek I, Zhang J, Shashikadze B, Stöckl JB, Bachter M, Bierschenk S, Renner S, Wolf E, Clauss S, Fröhlich T, Nickel AG, Maack C, Merkus D. Sen P, et al. Among authors: nickel ag. Basic Res Cardiol. 2026 Feb;121(1):93-112. doi: 10.1007/s00395-025-01153-6. Epub 2025 Dec 19. Basic Res Cardiol. 2026. PMID: 41419687 Free PMC article.
Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions.
Paulus MG, Renner K, Nickel AG, Brochhausen C, Limm K, Zügner E, Baier MJ, Pabel S, Wallner S, Birner C, Luchner A, Magnes C, Oefner PJ, Stark KJ, Wagner S, Maack C, Maier LS, Streckfuss-Bömeke K, Sossalla S, Dietl A. Paulus MG, et al. Among authors: nickel ag. Basic Res Cardiol. 2022 Sep 6;117(1):45. doi: 10.1007/s00395-022-00949-0. Basic Res Cardiol. 2022. PMID: 36068416 Free PMC article.
CaMKII does not control mitochondrial Ca2+ uptake in cardiac myocytes.
Nickel AG, Kohlhaas M, Bertero E, Wilhelm D, Wagner M, Sequeira V, Kreusser MM, Dewenter M, Kappl R, Hoth M, Dudek J, Backs J, Maack C. Nickel AG, et al. J Physiol. 2020 Apr;598(7):1361-1376. doi: 10.1113/JP276766. Epub 2019 Mar 27. J Physiol. 2020. PMID: 30770570 Free article.
Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure.
Nickel AG, von Hardenberg A, Hohl M, Löffler JR, Kohlhaas M, Becker J, Reil JC, Kazakov A, Bonnekoh J, Stadelmaier M, Puhl SL, Wagner M, Bogeski I, Cortassa S, Kappl R, Pasieka B, Lafontaine M, Lancaster CR, Blacker TS, Hall AR, Duchen MR, Kästner L, Lipp P, Zeller T, Müller C, Knopp A, Laufs U, Böhm M, Hoth M, Maack C. Nickel AG, et al. Cell Metab. 2015 Sep 1;22(3):472-84. doi: 10.1016/j.cmet.2015.07.008. Epub 2015 Aug 6. Cell Metab. 2015. PMID: 26256392 Free article.
Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice.
Hohl M, Mayr M, Lang L, Nickel AG, Barallobre-Barreiro J, Yin X, Speer T, Selejan SR, Goettsch C, Erb K, Fecher-Trost C, Reil JC, Linz B, Ruf S, Hübschle T, Maack C, Böhm M, Sadowski T, Linz D. Hohl M, et al. Among authors: nickel ag. J Biol Chem. 2020 Sep 4;295(36):12605-12617. doi: 10.1074/jbc.RA120.013488. Epub 2020 Jul 9. J Biol Chem. 2020. PMID: 32647007 Free PMC article.
13 results