Alexandrovich A - Search Results

1

Recessive TTN truncating mutations define novel forms of core myopathy with heart disease.

Chauveau C, Bonnemann CG, Julien C, Kho AL, Marks H, Talim B, Maury P, Arne-Bes MC, Uro-Coste E, Alexandrovich A, Vihola A, Schafer S, Kaufmann B, Medne L, Hübner N, Foley AR, Santi M, Udd B, Topaloglu H, Moore SA, Gotthardt M, Samuels ME, Gautel M, Ferreiro A. Chauveau C, et al. Among authors: alexandrovich a. Hum Mol Genet. 2014 Feb 15;23(4):980-91. doi: 10.1093/hmg/ddt494. Epub 2013 Oct 8. Hum Mol Genet. 2014. PMID: 24105469 Free PMC article.

2

Mechanoenzymatics of titin kinase.

Puchner EM, Alexandrovich A, Kho AL, Hensen U, Schäfer LV, Brandmeier B, Gräter F, Grubmüller H, Gaub HE, Gautel M. Puchner EM, et al. Among authors: alexandrovich a. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13385-90. doi: 10.1073/pnas.0805034105. Epub 2008 Sep 2. Proc Natl Acad Sci U S A. 2008. PMID: 18765796 Free PMC article.

3

A conditional gating mechanism assures the integrity of the molecular force-sensor titin kinase.

Stahl SW, Puchner EM, Alexandrovich A, Gautel M, Gaub HE. Stahl SW, et al. Among authors: alexandrovich a. Biophys J. 2011 Oct 19;101(8):1978-86. doi: 10.1016/j.bpj.2011.09.027. Biophys J. 2011. PMID: 22004752 Free PMC article.

4

The sarcomeric cytoskeleton as a target for pharmacological intervention.

Kho AL, Perera S, Alexandrovich A, Gautel M. Kho AL, et al. Among authors: alexandrovich a. Curr Opin Pharmacol. 2012 Jun;12(3):347-54. doi: 10.1016/j.coph.2012.03.007. Epub 2012 Apr 4. Curr Opin Pharmacol. 2012. PMID: 22483604 Review.

5

Molecular noise filtering in the β-adrenergic signaling network by phospholamban pentamers.

Koch D, Alexandrovich A, Funk F, Kho AL, Schmitt JP, Gautel M. Koch D, et al. Among authors: alexandrovich a. Cell Rep. 2021 Jul 27;36(4):109448. doi: 10.1016/j.celrep.2021.109448. Cell Rep. 2021. PMID: 34320358 Free PMC article.

6

Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase.

Baumann F, Bauer MS, Rees M, Alexandrovich A, Gautel M, Pippig DA, Gaub HE. Baumann F, et al. Among authors: alexandrovich a. Elife. 2017 Jul 11;6:e26473. doi: 10.7554/eLife.26473. Elife. 2017. PMID: 28696205 Free PMC article.

7

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro.

Koch D, Kho AL, Fukuzawa A, Alexandrovich A, Vanaanen KJ, Beavil A, Pfuhl M, Rees M, Gautel M. Koch D, et al. Among authors: alexandrovich a. PLoS One. 2023 Apr 20;18(4):e0284453. doi: 10.1371/journal.pone.0284453. eCollection 2023. PLoS One. 2023. PMID: 37079638 Free PMC article.

8

Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.

Rees M, Nikoopour R, Alexandrovich A, Pfuhl M, Lopes LR, Akhtar MM, Syrris P, Elliott P, Carr-White G, Gautel M. Rees M, et al. Among authors: alexandrovich a. J Struct Biol. 2023 Sep;215(3):108009. doi: 10.1016/j.jsb.2023.108009. Epub 2023 Aug 5. J Struct Biol. 2023. PMID: 37549721 Free PMC article.

9

High Throughput Screen Identifies Small Molecule Effectors That Modulate Thin Filament Activation in Cardiac Muscle.

Parijat P, Kondacs L, Alexandrovich A, Gautel M, Cobb AJA, Kampourakis T. Parijat P, et al. Among authors: alexandrovich a. ACS Chem Biol. 2021 Jan 15;16(1):225-235. doi: 10.1021/acschembio.0c00908. Epub 2020 Dec 14. ACS Chem Biol. 2021. PMID: 33315370

10

[No title available]

[No authors listed] [No authors listed] PMID: 36783437

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