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Page 1
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
The Cardiac Myofibroblast.
Alexanian M, Haldar SM. Alexanian M, et al. Circ Res. 2018 Dec 7;123(12):1258-1260. doi: 10.1161/CIRCRESAHA.118.314185. Circ Res. 2018. PMID: 30566054 Free PMC article. No abstract available.
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808
Transcription factor protein interactomes reveal genetic determinants in heart disease.
Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, Morton SU, McGregor M, Gifford CA, Seidman JG, Seidman CE, Gelb BD, Colombo G, Conklin BR, Black BL, Bruneau BG, Krogan NJ, Pollard KS, Srivastava D. Gonzalez-Teran B, et al. Among authors: alexanian m. Cell. 2022 Mar 3;185(5):794-814.e30. doi: 10.1016/j.cell.2022.01.021. Epub 2022 Feb 18. Cell. 2022. PMID: 35182466 Free PMC article.
The long noncoding RNA Wisper controls cardiac fibrosis and remodeling.
Micheletti R, Plaisance I, Abraham BJ, Sarre A, Ting CC, Alexanian M, Maric D, Maison D, Nemir M, Young RA, Schroen B, González A, Ounzain S, Pedrazzini T. Micheletti R, et al. Among authors: alexanian m. Sci Transl Med. 2017 Jun 21;9(395):eaai9118. doi: 10.1126/scitranslmed.aai9118. Sci Transl Med. 2017. PMID: 28637928 Free PMC article.
Long Noncoding RNAs in Cardiac Development.
Alexanian M, Ounzain S. Alexanian M, et al. Cold Spring Harb Perspect Biol. 2020 Nov 2;12(11):a037374. doi: 10.1101/cshperspect.a037374. Cold Spring Harb Perspect Biol. 2020. PMID: 31932317 Free PMC article. Review.
New Lncs to mesendoderm specification.
Alexanian M, Pedrazzini T, Ounzain S. Alexanian M, et al. J Thorac Dis. 2017 Mar;9(Suppl 1):S5-S8. doi: 10.21037/jtd.2017.03.70. J Thorac Dis. 2017. PMID: 28446963 Free PMC article. Review.
A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
Padmanabhan A, de Soysa TY, Pelonero A, Sapp V, Shah PP, Wang Q, Li L, Lee CY, Sadagopan N, Nishino T, Ye L, Yang R, Karnay A, Poleshko A, Bolar N, Linares-Saldana R, Ranade SS, Alexanian M, Morton SU, Jain M, Haldar SM, Srivastava D, Jain R. Padmanabhan A, et al. Among authors: alexanian m. Nat Cardiovasc Res. 2024 Mar;3(3):317-331. doi: 10.1038/s44161-024-00431-1. Epub 2024 Feb 23. Nat Cardiovasc Res. 2024. PMID: 39196112 Free PMC article.
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Lee CY, Sadagopan N, Huang Y, Pelonero A, Auclair K, Zhu A, Teran BG, Flanigan W, Kim CK, Lumbao-Conradson K, Costa M, Jain R, Charo I, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. bioRxiv [Preprint]. 2023 Jan 7:2023.01.06.522937. doi: 10.1101/2023.01.06.522937. bioRxiv. 2023. PMID: 36711864 Free PMC article. Preprint.
30 results