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Increased numbers of DNA-damaged spermatozoa in samples presenting an elevated rate of numerical chromosome abnormalities.
Enciso M, Alfarawati S, Wells D. Enciso M, et al. Among authors: alfarawati s. Hum Reprod. 2013 Jun;28(6):1707-15. doi: 10.1093/humrep/det077. Epub 2013 Mar 22. Hum Reprod. 2013. PMID: 23526303
The incidence and origin of segmental aneuploidy in human oocytes and preimplantation embryos.
Babariya D, Fragouli E, Alfarawati S, Spath K, Wells D. Babariya D, et al. Among authors: alfarawati s. Hum Reprod. 2017 Dec 1;32(12):2549-2560. doi: 10.1093/humrep/dex324. Hum Reprod. 2017. PMID: 29126206
Morphological and cytogenetic assessment of cleavage and blastocyst stage embryos.
Fragouli E, Alfarawati S, Spath K, Wells D. Fragouli E, et al. Among authors: alfarawati s. Mol Hum Reprod. 2014 Feb;20(2):117-26. doi: 10.1093/molehr/gat073. Epub 2013 Nov 1. Mol Hum Reprod. 2014. PMID: 24184690
Morphological assessments are the main way in which fertility clinics select in vitro generated embryo(s) for transfer to the uterus. ...
Morphological assessments are the main way in which fertility clinics select in vitro generated embryo(s) for transfer to the uterus. …
Comparative genomic hybridization of oocytes and first polar bodies from young donors.
Fragouli E, Escalona A, Gutiérrez-Mateo C, Tormasi S, Alfarawati S, Sepulveda S, Noriega L, Garcia J, Wells D, Munné S. Fragouli E, et al. Among authors: alfarawati s. Reprod Biomed Online. 2009 Aug;19(2):228-37. doi: 10.1016/s1472-6483(10)60078-8. Reprod Biomed Online. 2009. PMID: 19712560
First births after preimplantation genetic diagnosis of structural chromosome abnormalities using comparative genomic hybridization and microarray analysis.
Alfarawati S, Fragouli E, Colls P, Wells D. Alfarawati S, et al. Hum Reprod. 2011 Jun;26(6):1560-74. doi: 10.1093/humrep/der068. Epub 2011 Mar 29. Hum Reprod. 2011. PMID: 21447693
Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential.
Fragouli E, Spath K, Alfarawati S, Kaper F, Craig A, Michel CE, Kokocinski F, Cohen J, Munne S, Wells D. Fragouli E, et al. Among authors: alfarawati s. PLoS Genet. 2015 Jun 3;11(6):e1005241. doi: 10.1371/journal.pgen.1005241. eCollection 2015 Jun. PLoS Genet. 2015. PMID: 26039092 Free PMC article.
Simultaneous assessment of aneuploidy, polymorphisms, and mitochondrial DNA content in human polar bodies and embryos with the use of a novel microarray platform.
Konstantinidis M, Alfarawati S, Hurd D, Paolucci M, Shovelton J, Fragouli E, Wells D. Konstantinidis M, et al. Among authors: alfarawati s. Fertil Steril. 2014 Nov;102(5):1385-92. doi: 10.1016/j.fertnstert.2014.07.1233. Epub 2014 Sep 11. Fertil Steril. 2014. PMID: 25217868
The origin and impact of embryonic aneuploidy.
Fragouli E, Alfarawati S, Spath K, Jaroudi S, Sarasa J, Enciso M, Wells D. Fragouli E, et al. Among authors: alfarawati s. Hum Genet. 2013 Sep;132(9):1001-13. doi: 10.1007/s00439-013-1309-0. Epub 2013 Apr 26. Hum Genet. 2013. PMID: 23620267
Embryos of robertsonian translocation carriers exhibit a mitotic interchromosomal effect that enhances genetic instability during early development.
Alfarawati S, Fragouli E, Colls P, Wells D. Alfarawati S, et al. PLoS Genet. 2012;8(10):e1003025. doi: 10.1371/journal.pgen.1003025. Epub 2012 Oct 25. PLoS Genet. 2012. PMID: 23133396 Free PMC article.
The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidy.
Fragouli E, Alfarawati S, Goodall NN, Sánchez-García JF, Colls P, Wells D. Fragouli E, et al. Among authors: alfarawati s. Mol Hum Reprod. 2011 May;17(5):286-95. doi: 10.1093/molehr/gar024. Epub 2011 Apr 14. Mol Hum Reprod. 2011. PMID: 21493685
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