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Signature-based approaches for informed drug repurposing: targeting CNS disorders.
Shukla R, Henkel ND, Alganem K, Hamoud AR, Reigle J, Alnafisah RS, Eby HM, Imami AS, Creeden JF, Miruzzi SA, Meller J, Mccullumsmith RE. Shukla R, et al. Among authors: alganem k. Neuropsychopharmacology. 2021 Jan;46(1):116-130. doi: 10.1038/s41386-020-0752-6. Epub 2020 Jun 30. Neuropsychopharmacology. 2021. PMID: 32604402 Free PMC article. Review.
Hepatic kinome atlas: An in-depth identification of kinase pathways in liver fibrosis of humans and rodents.
Creeden JF, Kipp ZA, Xu M, Flight RM, Moseley HNB, Martinez GJ, Lee WH, Alganem K, Imami AS, McMullen MR, Roychowdhury S, Nawabi AM, Hipp JA, Softic S, Weinman SA, McCullumsmith R, Nagy LE, Hinds TD Jr. Creeden JF, et al. Among authors: alganem k. Hepatology. 2022 Nov;76(5):1376-1388. doi: 10.1002/hep.32467. Epub 2022 Apr 8. Hepatology. 2022. PMID: 35313030 Free PMC article.
Microcystin-LR (MC-LR) Triggers Inflammatory Responses in Macrophages.
Su RC, Breidenbach JD, Alganem K, Khalaf FK, French BW, Dube P, Malhotra D, McCullumsmith R, Presloid JB, Wooten RM, Kennedy DJ, Haller ST. Su RC, et al. Among authors: alganem k. Int J Mol Sci. 2021 Sep 14;22(18):9939. doi: 10.3390/ijms22189939. Int J Mol Sci. 2021. PMID: 34576099 Free PMC article.
Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.
Wu X, Shukla R, Alganem K, Zhang X, Eby HM, Devine EA, Depasquale E, Reigle J, Simmons M, Hahn MK, Au-Yeung C, Asgariroozbehani R, Hahn CG, Haroutunian V, Meller J, Meador-Woodruff J, McCullumsmith RE. Wu X, et al. Among authors: alganem k. Mol Psychiatry. 2021 Dec;26(12):7699-7708. doi: 10.1038/s41380-021-01205-y. Epub 2021 Jul 16. Mol Psychiatry. 2021. PMID: 34272489 Free PMC article.
21 results