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High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.
Sci Rep. 2018 Nov 22;8(1):17239. doi: 10.1038/s41598-018-35417-0.
Sci Rep. 2018.
PMID: 30467317
Free PMC article.
A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening.
Beshiri ML, Tice CM, Tran C, Nguyen HM, Sowalsky AG, Agarwal S, Jansson KH, Yang Q, McGowen KM, Yin J, Alilin AN, Karzai FH, Dahut WL, Corey E, Kelly K.
Beshiri ML, et al. Among authors: alilin an.
Clin Cancer Res. 2018 Sep 1;24(17):4332-4345. doi: 10.1158/1078-0432.CCR-18-0409. Epub 2018 May 10.
Clin Cancer Res. 2018.
PMID: 29748182
Free PMC article.
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EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis.
Li L, Ameri AH, Wang S, Jansson KH, Casey OM, Yang Q, Beshiri ML, Fang L, Lake RG, Agarwal S, Alilin AN, Xu W, Yin J, Kelly K.
Li L, et al. Among authors: alilin an.
Oncogene. 2019 Aug;38(35):6241-6255. doi: 10.1038/s41388-019-0873-8. Epub 2019 Jul 16.
Oncogene. 2019.
PMID: 31312026
Free PMC article.
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Targeting the PI3K/AKT Pathway Overcomes Enzalutamide Resistance by Inhibiting Induction of the Glucocorticoid Receptor.
Adelaiye-Ogala R, Gryder BE, Nguyen YTM, Alilin AN, Grayson AR, Bajwa W, Jansson KH, Beshiri ML, Agarwal S, Rodriguez-Nieves JA, Capaldo B, Kelly K, VanderWeele DJ.
Adelaiye-Ogala R, et al. Among authors: alilin an.
Mol Cancer Ther. 2020 Jul;19(7):1436-1447. doi: 10.1158/1535-7163.MCT-19-0936. Epub 2020 May 5.
Mol Cancer Ther. 2020.
PMID: 32371590
Free PMC article.
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Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models.
Agarwal S, Fang L, McGowen K, Yin J, Bowman J, Ku AT, Alilin AN, Corey E, Roudier MP, True LD, Dumpit R, Coleman I, Lee JK, Nelson PS, Capaldo BJ, Mariani A, Hoover C, Senatorov IS, Beshiri M, Sowalsky AG, Hurt EM, Kelly K.
Agarwal S, et al. Among authors: alilin an.
J Clin Invest. 2023 Nov 15;133(22):e162148. doi: 10.1172/JCI162148.
J Clin Invest. 2023.
PMID: 37725435
Free PMC article.
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