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Lymphangiogenesis and cancer metastasis.
Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K. Stacker SA, et al. Nat Rev Cancer. 2002 Aug;2(8):573-83. doi: 10.1038/nrc863. Nat Rev Cancer. 2002. PMID: 12154350 Review.
Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers.
Stacker SA, Stenvers K, Caesar C, Vitali A, Domagala T, Nice E, Roufail S, Simpson RJ, Moritz R, Karpanen T, Alitalo K, Achen MG. Stacker SA, et al. J Biol Chem. 1999 Nov 5;274(45):32127-36. doi: 10.1074/jbc.274.45.32127. J Biol Chem. 1999. PMID: 10542248
Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts.
Dashkevich A, Raissadati A, Syrjälä SO, Zarkada G, Keränen MA, Tuuminen R, Krebs R, Anisimov A, Jeltsch M, Leppänen VM, Alitalo K, Nykänen AI, Lemström KB. Dashkevich A, et al. Am J Transplant. 2016 Apr;16(4):1160-72. doi: 10.1111/ajt.13564. Epub 2015 Dec 21. Am J Transplant. 2016. PMID: 26689983
Tie receptors: new modulators of angiogenic and lymphangiogenic responses.
Jones N, Iljin K, Dumont DJ, Alitalo K. Jones N, et al. Nat Rev Mol Cell Biol. 2001 Apr;2(4):257-67. doi: 10.1038/35067005. Nat Rev Mol Cell Biol. 2001. PMID: 11283723 Review.
PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor.
Bergsten E, Uutela M, Li X, Pietras K, Ostman A, Heldin CH, Alitalo K, Eriksson U. Bergsten E, et al. Nat Cell Biol. 2001 May;3(5):512-6. doi: 10.1038/35074588. Nat Cell Biol. 2001. PMID: 11331881
Molecular mechanisms of lymphangiogenesis.
Mäkinen T, Alitalo K. Mäkinen T, et al. Cold Spring Harb Symp Quant Biol. 2002;67:189-96. doi: 10.1101/sqb.2002.67.189. Cold Spring Harb Symp Quant Biol. 2002. PMID: 12858540 Review. No abstract available.
A model for gene therapy of human hereditary lymphedema.
Karkkainen MJ, Saaristo A, Jussila L, Karila KA, Lawrence EC, Pajusola K, Bueler H, Eichmann A, Kauppinen R, Kettunen MI, Yla-Herttuala S, Finegold DN, Ferrell RE, Alitalo K. Karkkainen MJ, et al. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12677-82. doi: 10.1073/pnas.221449198. Epub 2001 Oct 9. Proc Natl Acad Sci U S A. 2001. PMID: 11592985 Free PMC article.
Lymphatic vessels as targets of tumor therapy?
Karpanen T, Alitalo K. Karpanen T, et al. J Exp Med. 2001 Sep 17;194(6):F37-42. doi: 10.1084/jem.194.6.f37. J Exp Med. 2001. PMID: 11561002 Free PMC article. Review. No abstract available.
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