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Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis.
Allan LA, Clarke PR. Allan LA, et al. Mol Cell. 2007 Apr 27;26(2):301-10. doi: 10.1016/j.molcel.2007.03.019. Mol Cell. 2007. PMID: 17466630
Destruction's our delight: controlling apoptosis during mitotic arrest.
Clarke PR, Allan LA. Clarke PR, et al. Among authors: allan la. Cell Cycle. 2010 Oct 15;9(20):4035-6. doi: 10.4161/cc.9.20.13522. Epub 2010 Oct 2. Cell Cycle. 2010. PMID: 20935484 No abstract available.
Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death.
Hou Y, Allan LA, Clarke PR. Hou Y, et al. Among authors: allan la. J Cell Sci. 2017 Jan 15;130(2):502-511. doi: 10.1242/jcs.192310. Epub 2016 Dec 7. J Cell Sci. 2017. PMID: 27927753 Free PMC article.
Prolonged mitotic arrest induces a caspase-dependent DNA damage response at telomeres that determines cell survival.
Hain KO, Colin DJ, Rastogi S, Allan LA, Clarke PR. Hain KO, et al. Among authors: allan la. Sci Rep. 2016 May 27;6:26766. doi: 10.1038/srep26766. Sci Rep. 2016. PMID: 27230693 Free PMC article.
Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins.
Colin DJ, Hain KO, Allan LA, Clarke PR. Colin DJ, et al. Among authors: allan la. Open Biol. 2015 Mar;5(3):140156. doi: 10.1098/rsob.140156. Open Biol. 2015. PMID: 25761368 Free PMC article.
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.
Harley ME, Allan LA, Sanderson HS, Clarke PR. Harley ME, et al. Among authors: allan la. EMBO J. 2010 Jul 21;29(14):2407-20. doi: 10.1038/emboj.2010.112. Epub 2010 Jun 4. EMBO J. 2010. PMID: 20526282 Free PMC article.
Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.
Allan LA, Clarke PR. Allan LA, et al. FEBS J. 2009 Nov;276(21):6063-73. doi: 10.1111/j.1742-4658.2009.07330.x. Epub 2009 Sep 29. FEBS J. 2009. PMID: 19788417 Review.
Cell-cycle control in the face of damage--a matter of life or death.
Clarke PR, Allan LA. Clarke PR, et al. Among authors: allan la. Trends Cell Biol. 2009 Mar;19(3):89-98. doi: 10.1016/j.tcb.2008.12.003. Epub 2009 Jan 23. Trends Cell Biol. 2009. PMID: 19168356 Review.
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.
Seifert A, Allan LA, Clarke PR. Seifert A, et al. Among authors: allan la. FEBS J. 2008 Dec;275(24):6268-80. doi: 10.1111/j.1742-4658.2008.06751.x. Epub 2008 Nov 7. FEBS J. 2008. PMID: 19016842
A mechanism coupling cell division and the control of apoptosis.
Allan LA, Clarke PR. Allan LA, et al. SEB Exp Biol Ser. 2008;59:257-65. SEB Exp Biol Ser. 2008. PMID: 18368928
Our recent results demonstrate that caspase activation is regulated during the cell cycle, establishing a direct link between the regulation of apoptosis and cell division (Allan and Clarke, 2007). ...
Our recent results demonstrate that caspase activation is regulated during the cell cycle, establishing a direct link between the regulation …
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