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Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.
McMurchy AN, Gillies J, Allan SE, Passerini L, Gambineri E, Roncarolo MG, Bacchetta R, Levings MK. McMurchy AN, et al. Among authors: allan se. J Allergy Clin Immunol. 2010 Dec;126(6):1242-51. doi: 10.1016/j.jaci.2010.09.001. Epub 2010 Oct 30. J Allergy Clin Immunol. 2010. PMID: 21036387
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, Ziegler SF, Roncarolo MG, Levings MK. Allan SE, et al. J Clin Invest. 2005 Nov;115(11):3276-84. doi: 10.1172/JCI24685. Epub 2005 Oct 6. J Clin Invest. 2005. PMID: 16211090 Free PMC article.
CD4+ T-regulatory cells: toward therapy for human diseases.
Allan SE, Broady R, Gregori S, Himmel ME, Locke N, Roncarolo MG, Bacchetta R, Levings MK. Allan SE, et al. Immunol Rev. 2008 Jun;223:391-421. doi: 10.1111/j.1600-065X.2008.00634.x. Immunol Rev. 2008. PMID: 18613849 Review.
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