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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Teijeira Á, Garasa S, Gato M, Alfaro C, Migueliz I, Cirella A, de Andrea C, Ochoa MC, Otano I, Etxeberria I, Andueza MP, Nieto CP, Resano L, Azpilikueta A, Allegretti M, de Pizzol M, Ponz-Sarvisé M, Rouzaut A, Sanmamed MF, Schalper K, Carleton M, Mellado M, Rodriguez-Ruiz ME, Berraondo P, Perez-Gracia JL, Melero I. Teijeira Á, et al. Among authors: allegretti m. Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13. Immunity. 2020. PMID: 32289253 Free article.
Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy.
Cristiano C, Giorgio C, Cocchiaro P, Boccella S, Cesta MC, Castelli V, Liguori FM, Cuozzo MR, Brandolini L, Russo R, Allegretti M. Cristiano C, et al. Among authors: allegretti m. Cytokine. 2023 Nov;171:156370. doi: 10.1016/j.cyto.2023.156370. Epub 2023 Sep 16. Cytokine. 2023. PMID: 37722320 Free article.
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
Bertini R, Allegretti M, Bizzarri C, Moriconi A, Locati M, Zampella G, Cervellera MN, Di Cioccio V, Cesta MC, Galliera E, Martinez FO, Di Bitondo R, Troiani G, Sabbatini V, D'Anniballe G, Anacardio R, Cutrin JC, Cavalieri B, Mainiero F, Strippoli R, Villa P, Di Girolamo M, Martin F, Gentile M, Santoni A, Corda D, Poli G, Mantovani A, Ghezzi P, Colotta F. Bertini R, et al. Among authors: allegretti m. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11791-6. doi: 10.1073/pnas.0402090101. Epub 2004 Jul 28. Proc Natl Acad Sci U S A. 2004. PMID: 15282370 Free PMC article.
Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling.
Brandolini L, Cristiano L, Fidoamore A, De Pizzol M, Di Giacomo E, Florio TM, Confalone G, Galante A, Cinque B, Benedetti E, Ruffini PA, Cifone MG, Giordano A, Alecci M, Allegretti M, Cimini A. Brandolini L, et al. Among authors: allegretti m. Oncotarget. 2015 Dec 22;6(41):43375-94. doi: 10.18632/oncotarget.6234. Oncotarget. 2015. PMID: 26517518 Free PMC article.
Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs).
Alfaro C, Teijeira A, Oñate C, Pérez G, Sanmamed MF, Andueza MP, Alignani D, Labiano S, Azpilikueta A, Rodriguez-Paulete A, Garasa S, Fusco JP, Aznar A, Inogés S, De Pizzol M, Allegretti M, Medina-Echeverz J, Berraondo P, Perez-Gracia JL, Melero I. Alfaro C, et al. Among authors: allegretti m. Clin Cancer Res. 2016 Aug 1;22(15):3924-36. doi: 10.1158/1078-0432.CCR-15-2463. Epub 2016 Mar 8. Clin Cancer Res. 2016. PMID: 26957562
Multiple anti-tumor effects of Reparixin on thyroid cancer.
Liotti F, De Pizzol M, Allegretti M, Prevete N, Melillo RM. Liotti F, et al. Among authors: allegretti m. Oncotarget. 2017 May 30;8(22):35946-35961. doi: 10.18632/oncotarget.16412. Oncotarget. 2017. PMID: 28415590 Free PMC article.
156 results