Allen A - Search Results

1

Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition.

Allen A, Qin ACR, Raj N, Wang J, Uddin S, Yao Z, Tang L, Meyers PA, Taylor BS, Berger MF, Yaeger R, Reidy-Lagunes D, Pratilas CA. Allen A, et al. PLoS One. 2019 Jun 3;14(6):e0217399. doi: 10.1371/journal.pone.0217399. eCollection 2019. PLoS One. 2019. PMID: 31158244 Free PMC article.

2

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAF^V600E-Mutant Brain Tumor.

Wang J, Yao Z, Jonsson P, Allen AN, Qin ACR, Uddin S, Dunkel IJ, Petriccione M, Manova K, Haque S, Rosenblum MK, Pisapia DJ, Rosen N, Taylor BS, Pratilas CA. Wang J, et al. Among authors: allen an. Cancer Discov. 2018 Sep;8(9):1130-1141. doi: 10.1158/2159-8290.CD-17-1263. Epub 2018 Jun 7. Cancer Discov. 2018. PMID: 29880583 Free PMC article.

3

Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors.

Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA. Wang J, et al. Among authors: allen an. Cancer Res. 2020 Dec 1;80(23):5367-5379. doi: 10.1158/0008-5472.CAN-20-1365. Epub 2020 Oct 8. Cancer Res. 2020. PMID: 33032988 Free PMC article.

4

Combination MEK and mTOR inhibitor therapy is active in models of glioblastoma.

Schreck KC, Allen AN, Wang J, Pratilas CA. Schreck KC, et al. Among authors: allen an. Neurooncol Adv. 2020 Oct 15;2(1):vdaa138. doi: 10.1093/noajnl/vdaa138. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33235998 Free PMC article.

5

Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAF^V600E-Mutant Human Glioma.

Schreck KC, Morin A, Zhao G, Allen AN, Flannery P, Glantz M, Green AL, Jones C, Jones KL, Kilburn LB, Nazemi KJ, Samuel D, Sanford B, Solomon DA, Wang J, Pratilas CA, Nicolaides T, Mulcahy Levy JM. Schreck KC, et al. Among authors: allen an. Clin Cancer Res. 2021 Nov 15;27(22):6197-6208. doi: 10.1158/1078-0432.CCR-21-2660. Epub 2021 Aug 25. Clin Cancer Res. 2021. PMID: 34433654 Free PMC article.

6

Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma.

Odeniyide P, Yohe ME, Pollard K, Vaseva AV, Calizo A, Zhang L, Rodriguez FJ, Gross JM, Allen AN, Wan X, Somwar R, Schreck KC, Kessler L, Wang J, Pratilas CA. Odeniyide P, et al. Among authors: allen an. Oncogene. 2022 May;41(21):2973-2983. doi: 10.1038/s41388-022-02305-x. Epub 2022 Apr 22. Oncogene. 2022. PMID: 35459782 Free PMC article.

7

Correction: Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma.

Odeniyide P, Yohe ME, Pollard K, Vaseva AV, Calizo A, Zhang L, Rodriguez FJ, Gross JM, Allen AN, Wan X, Somwar R, Schreck KC, Kessler L, Wang J, Pratilas CA. Odeniyide P, et al. Among authors: allen an. Oncogene. 2022 May;41(21):3037. doi: 10.1038/s41388-022-02342-6. Oncogene. 2022. PMID: 35534540 Free PMC article. No abstract available.

8

The novel cyclophilin binding compound, sanglifehrin A, disassociates G1 cell cycle arrest from tolerance induction.

Allen A, Zheng Y, Gardner L, Safford M, Horton MR, Powell JD. Allen A, et al. J Immunol. 2004 Apr 15;172(8):4797-803. doi: 10.4049/jimmunol.172.8.4797. J Immunol. 2004. PMID: 15067056

9

Egr-2 and Egr-3 are negative regulators of T cell activation.

Safford M, Collins S, Lutz MA, Allen A, Huang CT, Kowalski J, Blackford A, Horton MR, Drake C, Schwartz RH, Powell JD. Safford M, et al. Among authors: allen a. Nat Immunol. 2005 May;6(5):472-80. doi: 10.1038/ni1193. Epub 2005 Apr 17. Nat Immunol. 2005. PMID: 15834410

10

A role for mammalian target of rapamycin in regulating T cell activation versus anergy.

Zheng Y, Collins SL, Lutz MA, Allen AN, Kole TP, Zarek PE, Powell JD. Zheng Y, et al. Among authors: allen an. J Immunol. 2007 Feb 15;178(4):2163-70. doi: 10.4049/jimmunol.178.4.2163. J Immunol. 2007. PMID: 17277121

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