Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor.
Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Murray R, Prescott M, McNamara CW, Slayman CW, Amaro RE, Suzuki Y, Winzeler EA.
Goldgof GM, et al. Among authors: allen ke.
Sci Rep. 2016 Jun 13;6:27806. doi: 10.1038/srep27806.
Sci Rep. 2016.
PMID: 27291296
Free PMC article.