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A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex.
Aller P, Duclos S, Wallace SS, Doublié S. Aller P, et al. J Mol Biol. 2011 Sep 9;412(1):22-34. doi: 10.1016/j.jmb.2011.07.007. Epub 2011 Jul 18. J Mol Biol. 2011. PMID: 21781974 Free PMC article.
A previously solved structure of the bacteriophage RB69 DNA polymerase (RB69 gp43) in complex with Tg in the sequence context 5'-G-Tg-G shed light on how Tg blocks primer elongation: The protruding methyl group of the oxidized thymine displaces the adjacent 5'-G, which can no lon …
A previously solved structure of the bacteriophage RB69 DNA polymerase (RB69 gp43) in complex with Tg in the sequence context 5'-G-Tg-G shed …
5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases.
Le Bihan YV, Angeles Izquierdo M, Coste F, Aller P, Culard F, Gehrke TH, Essalhi K, Carell T, Castaing B. Le Bihan YV, et al. Among authors: aller p. Nucleic Acids Res. 2011 Aug;39(14):6277-90. doi: 10.1093/nar/gkr215. Epub 2011 Apr 12. Nucleic Acids Res. 2011. PMID: 21486746 Free PMC article.
Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118.
Lobley CM, Aller P, Douangamath A, Reddivari Y, Bumann M, Bird LE, Nettleship JE, Brandao-Neto J, Owens RJ, O'Toole PW, Walsh MA. Lobley CM, et al. Among authors: aller p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1427-33. doi: 10.1107/S174430911204273X. Epub 2012 Nov 14. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23192019 Free PMC article.
Applications of thin-film sandwich crystallization platforms.
Axford D, Aller P, Sanchez-Weatherby J, Sandy J. Axford D, et al. Among authors: aller p. Acta Crystallogr F Struct Biol Commun. 2016 Apr;72(Pt 4):313-9. doi: 10.1107/S2053230X16004386. Epub 2016 Mar 24. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27050266 Free PMC article.
Application of in situ diffraction in high-throughput structure determination platforms.
Aller P, Sanchez-Weatherby J, Foadi J, Winter G, Lobley CM, Axford D, Ashton AW, Bellini D, Brandao-Neto J, Culurgioni S, Douangamath A, Duman R, Evans G, Fisher S, Flaig R, Hall DR, Lukacik P, Mazzorana M, McAuley KE, Mykhaylyk V, Owen RL, Paterson NG, Romano P, Sandy J, Sorensen T, von Delft F, Wagner A, Warren A, Williams M, Stuart DI, Walsh MA. Aller P, et al. Methods Mol Biol. 2015;1261:233-53. doi: 10.1007/978-1-4939-2230-7_13. Methods Mol Biol. 2015. PMID: 25502203 Review.
118 results